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Treadmill exercise reduces α-synuclein spreading via PPARα

This study underlines the importance of treadmill exercise in reducing α-synuclein (α-syn) spreading in the A53T brain and protecting nigral dopaminergic neurons. Preformed α-syn fibril (PFF) seeding in the internal capsule of young A53T α-syn mice leads to increased spreading of α-syn to substantia...

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Detalles Bibliográficos
Autores principales:	Dutta, Debashis, Paidi, Ramesh Kumar, Raha, Sumita, Roy, Avik, Chandra, Sujyoti, Pahan, Kalipada
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308946/ https://www.ncbi.nlm.nih.gov/pubmed/35830804 http://dx.doi.org/10.1016/j.celrep.2022.111058

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