CXCL13-producing CD4(+) T cells accumulate in the early phase of tertiary lymphoid structures in ovarian cancer

Tertiary lymphoid structures (TLS) are transient ectopic lymphoid aggregates whose formation might be caused by chronic inflammation states, such as cancer. However, how TLS are induced in the tumor microenvironment (TME) and how they affect patient survival are not well understood. We investigated...

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Detalles Bibliográficos
Autores principales: Ukita, Masayo, Hamanishi, Junzo, Yoshitomi, Hiroyuki, Yamanoi, Koji, Takamatsu, Shiro, Ueda, Akihiko, Suzuki, Haruka, Hosoe, Yuko, Furutake, Yoko, Taki, Mana, Abiko, Kaoru, Yamaguchi, Ken, Nakai, Hidekatsu, Baba, Tsukasa, Matsumura, Noriomi, Yoshizawa, Akihiko, Ueno, Hideki, Mandai, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309049/
https://www.ncbi.nlm.nih.gov/pubmed/35552285
http://dx.doi.org/10.1172/jci.insight.157215

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