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Dichloroacetate improves systemic energy balance and feeding behavior during sepsis

Sepsis is a life-threatening organ dysfunction caused by dysregulated host response to an infection. The metabolic aberrations associated with sepsis underly an acute and organism-wide hyperinflammatory response and multiple organ dysfunction; however, crosstalk between systemic metabolomic alterati...

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Detalles Bibliográficos
Autores principales: Oh, Tae Seok, Zabalawi, Manal, Jain, Shalini, Long, David, Stacpoole, Peter W., McCall, Charles E., Quinn, Matthew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309051/
https://www.ncbi.nlm.nih.gov/pubmed/35730570
http://dx.doi.org/10.1172/jci.insight.153944