Blocking cell cycle progression through CDK4/6 protects against chronic kidney disease

Acute and chronic kidney injuries induce increased cell cycle progression in renal tubules. While increased cell cycle progression promotes repair after acute injury, the role of ongoing tubular cell cycle progression in chronic kidney disease is unknown. Two weeks after initiation of chronic kidney...

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Detalles Bibliográficos
Autores principales: Osaki, Yosuke, Manolopoulou, Marika, Ivanova, Alla V., Vartanian, Nicholas, Mignemi, Melanie Phillips, Kern, Justin, Chen, Jianchun, Yang, Haichun, Fogo, Agnes B., Zhang, Mingzhi, Robinson-Cohen, Cassianne, Gewin, Leslie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309053/
https://www.ncbi.nlm.nih.gov/pubmed/35730565
http://dx.doi.org/10.1172/jci.insight.158754

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