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STAT1 signaling protects self-reactive T cells from control by innate cells during neuroinflammation

The transcription factor STAT1 plays a critical role in modulating the differentiation of CD4(+) T cells producing IL-17 and GM-CSF, which promote the development of experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS). The protective role of STAT1 in MS and EA...

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Detalles Bibliográficos
Autores principales:	Arbelaez, Carlos A., Palle, Pushpalatha, Charaix, Jonathan, Bettelli, Estelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309063/ https://www.ncbi.nlm.nih.gov/pubmed/35587373 http://dx.doi.org/10.1172/jci.insight.148222

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