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Crosstalk of copper and zinc in the pathogenesis of vascular dementia

Copper and zinc are essential for normal brain functions. Both are localized in presynaptic vesicles and are secreted into synaptic clefts during neuronal excitation. Despite their significance, excesses of copper and zinc are neurotoxic. In particular, excess zinc after transient global ischemia pl...

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Detalles Bibliográficos
Autores principales: Kawahara, Masahiro, Tanaka, Ken-ichiro, Kato-Negishi, Midori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309079/
https://www.ncbi.nlm.nih.gov/pubmed/35903609
http://dx.doi.org/10.3164/jcbn.22-40