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The accumulation of copper in the brain of Down syndrome promotes oxidative stress: possible mechanism underlying cognitive impairment
Individuals with Down syndrome (DS), which is caused by triplication of human chromosome 21 (Hsa21), show numerous characteristic symptoms, such as intellectual disability, an impaired cognitive function, and accelerated aging-like phenotypes. Enhanced oxidative stress is assumed to be implicated as...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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the Society for Free Radical Research Japan
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309086/ https://www.ncbi.nlm.nih.gov/pubmed/35903608 http://dx.doi.org/10.3164/jcbn.21-155 |