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The antioxidative stress regulator Nrf2 potentiates radioresistance of oral squamous cell carcinoma accompanied with metabolic modulation
Nuclear factor erythroid 2-related factor 2 (Nrf2), which regulates the expression of critical antioxidant proteins, was recently demonstrated to play a key role in cancer progression. Resistance to radiotherapy is a major obstacle in treating oral squamous cell carcinoma (OSCC). However, little is...
Autores principales: | Matsuoka, Yuichiro, Yoshida, Ryoji, Kawahara, Kenta, Sakata, Junki, Arita, Hidetaka, Nkashima, Hikaru, Takahashi, Nozomu, Hirayama, Masatoshi, Nagata, Masashi, Hirosue, Akiyuki, Kuwahara, Yoshikazu, Fukumoto, Manabu, Toya, Ryo, Murakami, Ryuji, Nakayama, Hideki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309095/ https://www.ncbi.nlm.nih.gov/pubmed/35414650 http://dx.doi.org/10.1038/s41374-022-00776-w |
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