Cargando…

Identification of heptapeptides targeting a lethal bacterial strain in septic mice through an integrative approach

Effectively killing pathogenic bacteria is key for the treatment of sepsis. Although various anti-infective drugs have been used for the treatment of sepsis, the therapeutic effect is largely limited by the lack of a specific bacterium-targeting delivery system. This study aimed to develop antibacte...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Xiaoyan, Li, Shan, Luo, Haihua, He, Shuyue, Yang, Huangda, Li, Lei, Tian, Tian, Han, Qizheng, Ye, Jiacong, Huang, Chenyang, Liu, Aihua, Jiang, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309159/ https://www.ncbi.nlm.nih.gov/pubmed/35871689 http://dx.doi.org/10.1038/s41392-022-01035-6

Ejemplares similares

Identification of Radiotherapy-Associated Genes in Lung Adenocarcinoma by an Integrated Bioinformatics Analysis Approach
por: Wang, Junhao, et al.
Publicado: (2021)

Modified heptapeptide from tau binds both tubulin and microtubules
por: Li, Jingrui, et al.
Publicado: (2020)

Atomistic fibrillar architectures of polar prion-inspired heptapeptides
por: Peccati, Francesca, et al.
Publicado: (2020)

Anticancer Activities of Newly Synthesized Chiral Macrocyclic Heptapeptide Candidates
por: Abo-Ghalia, Mohamed H., et al.
Publicado: (2020)

TMBIM6, a potential virus target protein identified by integrated multiomics data analysis in SARS-CoV-2-infected host cells
por: Han, Qizheng, et al.
Publicado: (2021)

Effects of a Particular Heptapeptide on the IFN-α-Sensitive CML Cells
por: Yang, Fu-lan, et al.
Publicado: (2015)

Identification and Characterization of Novel Fc-Binding Heptapeptides from Experiments and Simulations
por: Sun, Xiaoquan, et al.
Publicado: (2018)

Screening of an annexin‐A2‐targeted heptapeptide for pancreatic adenocarcinoma localization
por: Ma, Heyao, et al.
Publicado: (2022)

Effect of TMAO and Urea on Dimers and Tetramers of Amyloidogenic Heptapeptides ((23)FGAILSS(29))
por: Khan, Ashma, et al.
Publicado: (2020)

The immunomodulatory functions and molecular mechanism of a new bursal heptapeptide (BP7) in immune responses and immature B cells
por: Feng, Xiu Li, et al.
Publicado: (2019)

Correction to: The immunomodulatory functions and molecular mechanism of a new bursal heptapeptide (BP7) in immune responses and immature B cells
por: Feng, Xiu Li, et al.
Publicado: (2021)

The Novel Property of Heptapeptide of Microcin C7 in Affecting the Cell Growth of Escherichia coli
por: Ran, Rensen, et al.
Publicado: (2017)

Identification of Specific Hydroxyapatite {001} Binding Heptapeptide by Phage Display and Its Nucleation Effect
por: Mao, Jing, et al.
Publicado: (2016)

Conformational Ensembles by NMR and MD Simulations in Model Heptapeptides with Select Tri-Peptide Motifs
por: Krishnan, V. V., et al.
Publicado: (2021)

Targeting adaptor protein SLP76 of RAGE as a therapeutic approach for lethal sepsis
por: Yan, Zhengzheng, et al.
Publicado: (2021)

Molecular basis for group-specific activation of the virulence regulator PlcR by PapR heptapeptides
por: Bouillaut, L., et al.
Publicado: (2008)

Bonnevillamides, Linear Heptapeptides Isolated from a Great Salt Lake-Derived Streptomyces sp.
por: Wu, Guangwei, et al.
Publicado: (2017)

Acylated heptapeptide binds albumin with high affinity and application as tag furnishes long-acting peptides
por: Zorzi, Alessandro, et al.
Publicado: (2017)

Exosomes Derived From Septic Mouse Serum Modulate Immune Responses via Exosome-Associated Cytokines
por: Gao, Kun, et al.
Publicado: (2019)

Integrated Analyses of Single-Cell Transcriptome and Mendelian Randomization Reveal the Protective Role of Resistin in Sepsis Survival in Intensive Care Unit
por: Chen, Hanghang, et al.
Publicado: (2023)

Cyclic heptapeptides with metal binding properties isolated from the fungus Cadophora malorum from Antarctic soil
por: Donalle, Guidmar C., et al.
Publicado: (2022)

XBP1 impacts lung adenocarcinoma progression by promoting plasma cell adaptation to the tumor microenvironment
por: Zhong, Zhaoqian, et al.
Publicado: (2022)

Polymeric nanoparticles conjugate a novel heptapeptide as an epidermal growth factor receptor-active targeting ligand for doxorubicin
por: Liu, Chia Wen, et al.
Publicado: (2012)

A Novel Carboxyl-Terminal Heptapeptide Initiates the Regulated Secretion of LH from Unique Sub-Domains of the ER
por: Jablonka-Shariff, Albina, et al.
Publicado: (2013)

Certain heptapeptide and large sequences representing an entire helix, strand or coil conformation in proteins are associated as chameleon sequences
por: Krishna, Neethu, et al.
Publicado: (2011)

An angiotensin-converting enzyme-2-derived heptapeptide GK-7 for SARS-CoV-2 spike blockade
por: Han, Songling, et al.
Publicado: (2021)

Purification and Characterization of a Novel Calcium-Binding Heptapeptide from the Hydrolysate of Tilapia Bone with Its Osteogenic Activity
por: He, Jinlun, et al.
Publicado: (2022)

Enhanced UHPLC-MS/MS determination of a therapeutic heptapeptide mimic for inflammatory-related diseases in rat plasma: application to a pharmacokinetic study
por: Li, Liang, et al.
Publicado: (2019)

Identification, Characterization and Antihypertensive Effect In Vivo of a Novel ACE-Inhibitory Heptapeptide from Defatted Areca Nut Kernel Globulin Hydrolysates
por: Liu, Xing, et al.
Publicado: (2021)

Multiplexed endoscopic imaging of Barrett’s neoplasia using targeted fluorescent heptapeptides in a phase 1 proof-of-concept study
por: Chen, Jing, et al.
Publicado: (2021)

A Novel Heptapeptide, GPPGPAG Transfers to the Brain, and Ameliorates Memory Dysfunction and Dendritic Atrophy in Alzheimer’s Disease Model Mice
por: Tohda, Chihiro, et al.
Publicado: (2021)

Talarolides Revisited: Cyclic Heptapeptides from an Australian Marine Tunicate-Associated Fungus, Talaromyces sp. CMB-TU011
por: Salim, Angela A., et al.
Publicado: (2023)

A slurry microcosm study on the interaction between antibiotics and soil bacterial community
por: Dong, Xiaohong, et al.
Publicado: (2020)

Selective Inhibition of SIRT2 Improves Outcomes in a Lethal Septic Model
por: Zhao, T., et al.
Publicado: (2015)

Synthesis of Linear and Cyclic Disulfide Heptapeptides of Longicalycinin A and Evaluation of Toxicity on Cancerous Cells HepG2 and HT-29
por: HoushdarTehrani, Mohammad Hassan, et al.
Publicado: (2018)

Brain-targeted heptapeptide-loaded exosomes attenuated ischemia–reperfusion injury by promoting the transfer of healthy mitochondria from astrocytes to neurons
por: Liu, Wei, et al.
Publicado: (2022)

The Correlation Between the Types of Initial Bacterial Infection and Clinical Prognosis in Patients With Septic AKI
por: Li, Tian, et al.
Publicado: (2022)

Histidine-rich glycoprotein prevents septic lethality through neutrophil regulation
por: Nishibori, M, et al.
Publicado: (2014)

Heptapeptide Isolated from Isochrysis zhanjiangensis Exhibited Anti-Photoaging Potential via MAPK/AP-1/MMP Pathway and Anti-Apoptosis in UVB-Irradiated HaCaT Cells
por: Zheng, Zhaowan, et al.
Publicado: (2021)

Protective effect of Cl-amidine against CLP-induced lethal septic shock in mice
por: Zhao, Ting, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_pmf09u8g2ht2tkas2r7ngsot44