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Autophagy Related Noncoding RNAs: Emerging Regulatory Factors of Gastric Cancer
Gastric cancer (GC) is one of the most common malignant cancers that seriously affect human health. Autophagy is a highly conserved self-defense mechanism found to plays an important role in the occurrence, progression, drug resistance, and prognosis of GC. Noncoding RNAs (ncRNAs) play a critical ro...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309173/ https://www.ncbi.nlm.nih.gov/pubmed/35898946 http://dx.doi.org/10.2147/CMAR.S364761 |
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author | Lu, Ling Liang, Qiaoyan Zhang, Xinyi Xu, Yumeng Meng, Dehua Liang, Zhaofeng |
author_facet | Lu, Ling Liang, Qiaoyan Zhang, Xinyi Xu, Yumeng Meng, Dehua Liang, Zhaofeng |
author_sort | Lu, Ling |
collection | PubMed |
description | Gastric cancer (GC) is one of the most common malignant cancers that seriously affect human health. Autophagy is a highly conserved self-defense mechanism found to plays an important role in the occurrence, progression, drug resistance, and prognosis of GC. Noncoding RNAs (ncRNAs) play a critical role in the occurrence and development of a variety of diseases including GC. In recent years, increasing attention has been given to research on autophagy-related ncRNAs, such as miRNA, lncRNA, and circRNA in GC. Herein, we briefly summarize the roles, functions, and the research progress of autophagy and autophagy-related ncRNAs in GC with a focus on the potential application in GC tumorigenesis, development, prognosis, and drug resistance. We also discussed prospects of clinical application, future research direction, and challenges in future research of autophagy-related ncRNAs. |
format | Online Article Text |
id | pubmed-9309173 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-93091732022-07-26 Autophagy Related Noncoding RNAs: Emerging Regulatory Factors of Gastric Cancer Lu, Ling Liang, Qiaoyan Zhang, Xinyi Xu, Yumeng Meng, Dehua Liang, Zhaofeng Cancer Manag Res Review Gastric cancer (GC) is one of the most common malignant cancers that seriously affect human health. Autophagy is a highly conserved self-defense mechanism found to plays an important role in the occurrence, progression, drug resistance, and prognosis of GC. Noncoding RNAs (ncRNAs) play a critical role in the occurrence and development of a variety of diseases including GC. In recent years, increasing attention has been given to research on autophagy-related ncRNAs, such as miRNA, lncRNA, and circRNA in GC. Herein, we briefly summarize the roles, functions, and the research progress of autophagy and autophagy-related ncRNAs in GC with a focus on the potential application in GC tumorigenesis, development, prognosis, and drug resistance. We also discussed prospects of clinical application, future research direction, and challenges in future research of autophagy-related ncRNAs. Dove 2022-07-19 /pmc/articles/PMC9309173/ /pubmed/35898946 http://dx.doi.org/10.2147/CMAR.S364761 Text en © 2022 Lu et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Review Lu, Ling Liang, Qiaoyan Zhang, Xinyi Xu, Yumeng Meng, Dehua Liang, Zhaofeng Autophagy Related Noncoding RNAs: Emerging Regulatory Factors of Gastric Cancer |
title | Autophagy Related Noncoding RNAs: Emerging Regulatory Factors of Gastric Cancer |
title_full | Autophagy Related Noncoding RNAs: Emerging Regulatory Factors of Gastric Cancer |
title_fullStr | Autophagy Related Noncoding RNAs: Emerging Regulatory Factors of Gastric Cancer |
title_full_unstemmed | Autophagy Related Noncoding RNAs: Emerging Regulatory Factors of Gastric Cancer |
title_short | Autophagy Related Noncoding RNAs: Emerging Regulatory Factors of Gastric Cancer |
title_sort | autophagy related noncoding rnas: emerging regulatory factors of gastric cancer |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309173/ https://www.ncbi.nlm.nih.gov/pubmed/35898946 http://dx.doi.org/10.2147/CMAR.S364761 |
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