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The integration of AlphaFold-predicted and crystal structures of human trans-3-hydroxy-l-proline dehydratase reveals a regulatory catalytic mechanism

Computational methods for protein structure prediction have made significant strides forward, as evidenced by the last development of the neural network AlphaFold, which outperformed the CASP14 competitors by consistently predicting the structure of target proteins. Here we show an integrated struct...

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Detalles Bibliográficos
Autores principales: Ferrario, Eugenio, Miggiano, Riccardo, Rizzi, Menico, Ferraris, Davide M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309405/
https://www.ncbi.nlm.nih.gov/pubmed/35891782
http://dx.doi.org/10.1016/j.csbj.2022.07.027