Mitosis of hepatitis B virus-infected cells in vitro results in uninfected daughter cells

BACKGROUND & AIMS: The chronicity of HBV (and resultant liver disease) is determined by intrahepatic persistence of the HBV covalently closed circular DNA (cccDNA), an episomal form that encodes all viral transcripts. Therefore, cccDNA is a key target for new treatments, with the ultimate therap...

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Detalles Bibliográficos
Autores principales: Tu, Thomas, Zehnder, Benno, Wettengel, Jochen M., Zhang, Henrik, Coulter, Sally, Ho, Vikki, Douglas, Mark W., Protzer, Ulrike, George, Jacob, Urban, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309680/
https://www.ncbi.nlm.nih.gov/pubmed/35898957
http://dx.doi.org/10.1016/j.jhepr.2022.100514

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