Cargando…

Incidence, Morbidity and years Lived With Disability due to Type 2 Diabetes Mellitus in 204 Countries and Territories: Trends From 1990 to 2019

BACKGROUND: We aimed to examine the descriptive epidemiology and trends in the burden of type 2 diabetes mellitus (T2DM). METHODS: Data were extracted from the Global Burden of Disease 2019 dataset. Estimated annual percentage changes (EAPCs) were calculated to assess the trends in incidence rate, m...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Rongrong, Zhou, Shan, Xia, Liang, Bao, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309695/
https://www.ncbi.nlm.nih.gov/pubmed/35898461
http://dx.doi.org/10.3389/fendo.2022.905538
_version_ 1784753224058667008
author Zhu, Rongrong
Zhou, Shan
Xia, Liang
Bao, Xiaoming
author_facet Zhu, Rongrong
Zhou, Shan
Xia, Liang
Bao, Xiaoming
author_sort Zhu, Rongrong
collection PubMed
description BACKGROUND: We aimed to examine the descriptive epidemiology and trends in the burden of type 2 diabetes mellitus (T2DM). METHODS: Data were extracted from the Global Burden of Disease 2019 dataset. Estimated annual percentage changes (EAPCs) were calculated to assess the trends in incidence rate, mortality and disability-adjusted life-years (DALYs) associated with T2DM. Measures were stratified by sex, region, country, age and social development index (SDI) value. RESULTS: The global age-standardized incidence rate of T2DM increased from 1990 to 2019, with an EAPC of 1.25 (95% CI, 1.19 to 1.31). In 2019, the highest age-standardized incidence rate of T2DM was observed in high-SDI regions, and the largest increase in this rate from 1990 to 2019 was also in high-SDI regions (EAPC, 1.74;95% CI, 1.57 to 1.90). At the regional level, Central Asia (EAPC, 2.53;95% CI, 2.45 to 2.61) had the largest increase in the age-standardized incidence rate of T2DM from 1990 to 2019. At the national level, Luxembourg (EAPC, 4.51;95% CI, 4.37 to 4.65) and Uzbekistan (EAPC, 3.63; 95% CI, 3.44 to 3.82) had the largest increases in the age-standardized incidence rate of T2DM from 1990 to 2019. The global age-standardized death and DALY rates increased from 1990 to 2019, with EAPCs of 0.26 (95% CI, 0.16 to 0.37) and 0.81 (95% CI, 0.77 to 0.85), respectively. The age-standardized death and DALY rates showed the largest increases in Central Asia, South Asia and Southern Sub-Saharan Africa. CONCLUSIONS: Globally, the age-standardized incidence, death and DALY rates increased from 1990 to 2019. Central Asia, South Asia and Southern Sub-Saharan Africa were found to have the greatest burden of T2DM. Future strategies should focus on these high-risk regions and other high-risk populations.
format Online
Article
Text
id pubmed-9309695
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-93096952022-07-26 Incidence, Morbidity and years Lived With Disability due to Type 2 Diabetes Mellitus in 204 Countries and Territories: Trends From 1990 to 2019 Zhu, Rongrong Zhou, Shan Xia, Liang Bao, Xiaoming Front Endocrinol (Lausanne) Endocrinology BACKGROUND: We aimed to examine the descriptive epidemiology and trends in the burden of type 2 diabetes mellitus (T2DM). METHODS: Data were extracted from the Global Burden of Disease 2019 dataset. Estimated annual percentage changes (EAPCs) were calculated to assess the trends in incidence rate, mortality and disability-adjusted life-years (DALYs) associated with T2DM. Measures were stratified by sex, region, country, age and social development index (SDI) value. RESULTS: The global age-standardized incidence rate of T2DM increased from 1990 to 2019, with an EAPC of 1.25 (95% CI, 1.19 to 1.31). In 2019, the highest age-standardized incidence rate of T2DM was observed in high-SDI regions, and the largest increase in this rate from 1990 to 2019 was also in high-SDI regions (EAPC, 1.74;95% CI, 1.57 to 1.90). At the regional level, Central Asia (EAPC, 2.53;95% CI, 2.45 to 2.61) had the largest increase in the age-standardized incidence rate of T2DM from 1990 to 2019. At the national level, Luxembourg (EAPC, 4.51;95% CI, 4.37 to 4.65) and Uzbekistan (EAPC, 3.63; 95% CI, 3.44 to 3.82) had the largest increases in the age-standardized incidence rate of T2DM from 1990 to 2019. The global age-standardized death and DALY rates increased from 1990 to 2019, with EAPCs of 0.26 (95% CI, 0.16 to 0.37) and 0.81 (95% CI, 0.77 to 0.85), respectively. The age-standardized death and DALY rates showed the largest increases in Central Asia, South Asia and Southern Sub-Saharan Africa. CONCLUSIONS: Globally, the age-standardized incidence, death and DALY rates increased from 1990 to 2019. Central Asia, South Asia and Southern Sub-Saharan Africa were found to have the greatest burden of T2DM. Future strategies should focus on these high-risk regions and other high-risk populations. Frontiers Media S.A. 2022-07-11 /pmc/articles/PMC9309695/ /pubmed/35898461 http://dx.doi.org/10.3389/fendo.2022.905538 Text en Copyright © 2022 Zhu, Zhou, Xia and Bao https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Zhu, Rongrong
Zhou, Shan
Xia, Liang
Bao, Xiaoming
Incidence, Morbidity and years Lived With Disability due to Type 2 Diabetes Mellitus in 204 Countries and Territories: Trends From 1990 to 2019
title Incidence, Morbidity and years Lived With Disability due to Type 2 Diabetes Mellitus in 204 Countries and Territories: Trends From 1990 to 2019
title_full Incidence, Morbidity and years Lived With Disability due to Type 2 Diabetes Mellitus in 204 Countries and Territories: Trends From 1990 to 2019
title_fullStr Incidence, Morbidity and years Lived With Disability due to Type 2 Diabetes Mellitus in 204 Countries and Territories: Trends From 1990 to 2019
title_full_unstemmed Incidence, Morbidity and years Lived With Disability due to Type 2 Diabetes Mellitus in 204 Countries and Territories: Trends From 1990 to 2019
title_short Incidence, Morbidity and years Lived With Disability due to Type 2 Diabetes Mellitus in 204 Countries and Territories: Trends From 1990 to 2019
title_sort incidence, morbidity and years lived with disability due to type 2 diabetes mellitus in 204 countries and territories: trends from 1990 to 2019
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309695/
https://www.ncbi.nlm.nih.gov/pubmed/35898461
http://dx.doi.org/10.3389/fendo.2022.905538
work_keys_str_mv AT zhurongrong incidencemorbidityandyearslivedwithdisabilityduetotype2diabetesmellitusin204countriesandterritoriestrendsfrom1990to2019
AT zhoushan incidencemorbidityandyearslivedwithdisabilityduetotype2diabetesmellitusin204countriesandterritoriestrendsfrom1990to2019
AT xialiang incidencemorbidityandyearslivedwithdisabilityduetotype2diabetesmellitusin204countriesandterritoriestrendsfrom1990to2019
AT baoxiaoming incidencemorbidityandyearslivedwithdisabilityduetotype2diabetesmellitusin204countriesandterritoriestrendsfrom1990to2019