The Deubiquitinase USP13 Maintains Cancer Cell Stemness by Promoting FASN Stability in Small Cell Lung Cancer

USP13 is significantly amplified in over 20% of lung cancer patients and critical for tumor progression. However, the functional role of USP13 in small cell lung cancer (SCLC) remains largely unclear. In this study, we found that the deubiquitinase USP13 is highly expressed in SCLC tumor samples and...

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Detalles Bibliográficos
Autores principales: Wang, Juhong, Lin, Weihao, Li, Renda, Cheng, Hong, Sun, Sijin, Shao, Fei, Yang, Yannan, Zhang, Lin, Feng, Xiaoli, Gao, Shugeng, Gao, Yibo, He, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309731/
https://www.ncbi.nlm.nih.gov/pubmed/35898882
http://dx.doi.org/10.3389/fonc.2022.899987

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