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Tumor Cell-Specific and Lipase-Responsive Delivery of Hydrogen Sulfide for Sensitizing Chemotherapy of Pancreatic Cancer

The inability of small molecule drugs to diffuse into tumor interstitium is responsible for the relatively low effectiveness of chemotherapy. Herein, a hydrogen sulfide (H(2)S) gas–involved chemosensitization strategy is proposed for pancreatic cancer treatment by developing a tumor-specific lipase-...

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Detalles Bibliográficos
Autores principales:	Tian, Libing, Pei, Rui, Zhang, Xiaojun, Li, Kun, Zhong, Yuting, Luo, Yougen, Zhou, Shu-Feng, Chen, Lichan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309817/ https://www.ncbi.nlm.nih.gov/pubmed/35898641 http://dx.doi.org/10.3389/fbioe.2022.934151

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