Cargando…

A Review on the Antidiabetic Properties of Moringa oleifera Extracts: Focusing on Oxidative Stress and Inflammation as Main Therapeutic Targets

Moringa oleifera is one of the popular plants that have shown significant health benefits. Certainly, preclinical evidence (predominantly from animal models) summarized in the current review supports the beneficial effects of Moringa oleifera leaf extracts in combating the prominent characteristic f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mthiyane, Fikile T., Dludla, Phiwayinkosi V., Ziqubu, Khanyisani, Mthembu, Sinenhlanhla X. H., Muvhulawa, Ndivhuwo, Hlengwa, Nokulunga, Nkambule, Bongani B., Mazibuko-Mbeje, Sithandiwe E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310029/ https://www.ncbi.nlm.nih.gov/pubmed/35899107 http://dx.doi.org/10.3389/fphar.2022.940572

Ejemplares similares

Corrigendum: A review on the antidiabetic properties of Moringa oleifera extracts: Focusing on oxidative stress and inflammation as main therapeutic targets
por: Mthiyane, Fikile T., et al.
Publicado: (2023)

Orientin Improves Substrate Utilization and the Expression of Major Genes Involved in Insulin Signaling and Energy Regulation in Cultured Insulin-Resistant Liver Cells
por: Mazibuko-Mbeje, Sithandiwe E., et al.
Publicado: (2021)

An insight into brown/beige adipose tissue whitening, a metabolic complication of obesity with the multifactorial origin
por: Ziqubu, Khanyisani, et al.
Publicado: (2023)

Detrimental Effects of Lipid Peroxidation in Type 2 Diabetes: Exploring the Neutralizing Influence of Antioxidants
por: Shabalala, Samukelisiwe C., et al.
Publicado: (2022)

Anti-Obesity Effects of Metformin: A Scoping Review Evaluating the Feasibility of Brown Adipose Tissue as a Therapeutic Target
por: Ziqubu, Khanyisani, et al.
Publicado: (2023)

The Potential Role of Polyphenols in Modulating Mitochondrial Bioenergetics within the Skeletal Muscle: A Systematic Review of Preclinical Models
por: Mthembu, Sinenhlanhla X. H., et al.
Publicado: (2021)

Bioactive Properties, Bioavailability Profiles, and Clinical Evidence of the Potential Benefits of Black Pepper (Piper nigrum) and Red Pepper (Capsicum annum) against Diverse Metabolic Complications
por: Dludla, Phiwayinkosi V., et al.
Publicado: (2023)

Potential Benefits of Coffee Consumption on Improving Biomarkers of Oxidative Stress and Inflammation in Healthy Individuals and Those at Increased Risk of Cardiovascular Disease
por: Dludla, Phiwayinkosi V., et al.
Publicado: (2023)

Pancreatic β-cell dysfunction in type 2 diabetes: Implications of inflammation and oxidative stress
por: Dludla, Phiwayinkosi V, et al.
Publicado: (2023)

Drug-Induced Liver Injury: Clinical Evidence of N-Acetyl Cysteine Protective Effects
por: Ntamo, Yonela, et al.
Publicado: (2021)

Dietary Supplements Potentially Target Plasma Glutathione Levels to Improve Cardiometabolic Health in Patients with Diabetes Mellitus: A Systematic Review of Randomized Clinical Trials
por: Dludla, Phiwayinkosi V., et al.
Publicado: (2023)

Impact of Isoorientin on Metabolic Activity and Lipid Accumulation in Differentiated Adipocytes
por: Ziqubu, Khanyisani, et al.
Publicado: (2020)

A systematic review exploring the significance of measuring epicardial fat thickness in correlation to B-type natriuretic peptide levels as prognostic and diagnostic markers in patients with or at risk of heart failure
por: Nyawo, Thembeka A., et al.
Publicado: (2021)

N-Acetyl Cysteine Targets Hepatic Lipid Accumulation to Curb Oxidative Stress and Inflammation in NAFLD: A Comprehensive Analysis of the Literature
por: Dludla, Phiwayinkosi V., et al.
Publicado: (2020)

Physical Exercise Potentially Targets Epicardial Adipose Tissue to Reduce Cardiovascular Disease Risk in Patients with Metabolic Diseases: Oxidative Stress and Inflammation Emerge as Major Therapeutic Targets
por: Nyawo, Thembeka A., et al.
Publicado: (2021)

Natural killer cell levels in adults living with type 2 diabetes: a systematic review and meta-analysis of clinical studies
por: Mxinwa, Vuyolwethu, et al.
Publicado: (2020)

Rooibos Flavonoids, Aspalathin, Isoorientin, and Orientin Ameliorate Antimycin A-Induced Mitochondrial Dysfunction by Improving Mitochondrial Bioenergetics in Cultured Skeletal Muscle Cells
por: Mthembu, Sinenhlanhla X. H., et al.
Publicado: (2021)

Vitamin C intake potentially lowers total cholesterol to improve endothelial function in diabetic patients at increased risk of cardiovascular disease: A systematic review of randomized controlled trials
por: Dludla, Phiwayinkosi V., et al.
Publicado: (2022)

Isoorientin ameliorates lipid accumulation by regulating fat browning in palmitate-exposed 3T3-L1 adipocytes
por: Mazibuko-Mbeje, Sithandiwe E., et al.
Publicado: (2020)

Aspalathin, a natural product with the potential to reverse hepatic insulin resistance by improving energy metabolism and mitochondrial respiration
por: Mazibuko-Mbeje, Sithandiwe E., et al.
Publicado: (2019)

Pathological Role of Oxidative Stress in Aflatoxin-Induced Toxicity in Different Experimental Models and Protective Effect of Phytochemicals: A Review
por: Jobe, Martha Cebile, et al.
Publicado: (2023)

Inflammation and Oxidative Stress in an Obese State and the Protective Effects of Gallic Acid
por: Dludla, Phiwayinkosi V., et al.
Publicado: (2018)

A Meta-Analysis of the Impact of Resveratrol Supplementation on Markers of Renal Function and Blood Pressure in Type 2 Diabetic Patients on Hypoglycemic Therapy
por: Nyambuya, Tawanda M., et al.
Publicado: (2020)

N-Acetyl cysteine ameliorates hyperglycemia-induced cardiomyocyte toxicity by improving mitochondrial energetics and enhancing endogenous Coenzyme Q(9/10) levels
por: Dludla, Phiwayinkosi V., et al.
Publicado: (2019)

Exploring the Comparative Efficacy of Metformin and Resveratrol in the Management of Diabetes-Associated Complications: A Systematic Review of Preclinical Studies
por: Dludla, Phiwayinkosi V., et al.
Publicado: (2020)

Coenzyme Q(10) Supplementation Improves Adipokine Levels and Alleviates Inflammation and Lipid Peroxidation in Conditions of Metabolic Syndrome: A Meta-Analysis of Randomized Controlled Trials
por: Dludla, Phiwayinkosi V., et al.
Publicado: (2020)

The prophylactic effects of vitamin K supplementation on coagulopathies associated with type 2 diabetes mellitus: A protocol for a systematic review and meta-analysis
por: Mokgalaboni, Kabelo, et al.
Publicado: (2020)

Pharmacological effects of statins in adult patients with type 2 diabetes mellitus: A protocol for systematic review and meta-analysis
por: Mokgalaboni, Kabelo, et al.
Publicado: (2022)

The Combination Effect of Aspalathin and Phenylpyruvic Acid-2-O-β-d-glucoside from Rooibos against Hyperglycemia-Induced Cardiac Damage: An In Vitro Study
por: Dludla, Phiwayinkosi V., et al.
Publicado: (2020)

T cell activation and cardiovascular risk in type 2 diabetes mellitus: a protocol for a systematic review and meta-analysis
por: Nyambuya, Tawanda M., et al.
Publicado: (2018)

Diet-Induced Obesity Promotes the Upregulation of Fas Expression on T-cells
por: Nyambuya, Tawanda Maurice, et al.
Publicado: (2021)

Investigating cardiovascular risk in premenopausal women on oral contraceptives: Systematic review with meta-analysis
por: Fabunmi, Oyesanmi A., et al.
Publicado: (2023)

Dietary supplementation of low levels of unprocessed Mucuna pruriens utilis seed meal induces mild antinutritional entero-physio-metabolic perturbations without compromising performance and meat quality in finisher broilers
por: Zungu, Pretty Ntombizethu, et al.
Publicado: (2023)

Platelet function and cardiovascular risk in adult HIV-infected patients on HAART: a protocol for a systematic review and meta-analysis
por: Nkambule, Bongani Brian, et al.
Publicado: (2017)

Impaired Glucose Tolerance is Associated with Enhanced Platelet-Monocyte Aggregation in Short-Term High-Fat Diet-Fed Mice
por: Mkandla, Zibusiso, et al.
Publicado: (2019)

Aspalathin-Enriched Green Rooibos Extract Reduces Hepatic Insulin Resistance by Modulating PI3K/AKT and AMPK Pathways
por: Mazibuko-Mbeje, Sithandiwe E., et al.
Publicado: (2019)

Cardioprotective potential of N-acetyl cysteine against hyperglycaemia-induced oxidative damage: a protocol for a systematic review
por: Dludla, Phiwayinkosi V., et al.
Publicado: (2017)

The role of innate lymphoid cells and T helper cell activation in type 2 diabetic patients: a protocol for a systematic review and meta-analysis
por: Mxinwa, Vuyolwethu, et al.
Publicado: (2019)

Obesity-induced inflammation and insulin resistance: A mini-review on T-cells
por: Nyambuya, Tawanda Maurice, et al.
Publicado: (2019)

A systematic review and meta-analysis on the regulation of programmed cell death-1 on T-cells in type 2 diabetes
por: Nyambuya, Tawanda Maurice, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_d5egpp1uc0o20uaii2clsurpj6