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Real-time echocardiography image analysis and quantification of cardiac indices

Deep learning has a huge potential to transform echocardiography in clinical practice and point of care ultrasound testing by providing real-time analysis of cardiac structure and function. Automated echocardiography analysis is benefited through use of machine learning for tasks such as image quali...

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Autores principales: Zamzmi, Ghada, Rajaraman, Sivaramakrishnan, Hsu, Li-Yueh, Sachdev, Vandana, Antani, Sameer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310146/
https://www.ncbi.nlm.nih.gov/pubmed/35868819
http://dx.doi.org/10.1016/j.media.2022.102438
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author Zamzmi, Ghada
Rajaraman, Sivaramakrishnan
Hsu, Li-Yueh
Sachdev, Vandana
Antani, Sameer
author_facet Zamzmi, Ghada
Rajaraman, Sivaramakrishnan
Hsu, Li-Yueh
Sachdev, Vandana
Antani, Sameer
author_sort Zamzmi, Ghada
collection PubMed
description Deep learning has a huge potential to transform echocardiography in clinical practice and point of care ultrasound testing by providing real-time analysis of cardiac structure and function. Automated echocardiography analysis is benefited through use of machine learning for tasks such as image quality assessment, view classification, cardiac region segmentation, and quantification of diagnostic indices. By taking advantage of high-performing deep neural networks, we propose a novel and eicient real-time system for echocardiography analysis and quantification. Our system uses a self-supervised modality-specific representation trained using a publicly available large-scale dataset. The trained representation is used to enhance the learning of target echo tasks with relatively small datasets. We also present a novel Trilateral Attention Network (TaNet) for real-time cardiac region segmentation. The proposed network uses a module for region localization and three lightweight pathways for encoding rich low-level, textural, and high-level features. Feature embeddings from these individual pathways are then aggregated for cardiac region segmentation. This network is fine-tuned using a joint loss function and training strategy. We extensively evaluate the proposed system and its components, which are echo view retrieval, cardiac segmentation, and quantification, using four echocardiography datasets. Our experimental results show a consistent improvement in the performance of echocardiography analysis tasks with enhanced computational eiciency that charts a path toward its adoption in clinical practice. Specifically, our results show superior real-time performance in retrieving good quality echo from individual cardiac view, segmenting cardiac chambers with complex overlaps, and extracting cardiac indices that highly agree with the experts’ values. The source code of our implementation can be found in the project ‘ s GitHub page.
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spelling pubmed-93101462022-08-01 Real-time echocardiography image analysis and quantification of cardiac indices Zamzmi, Ghada Rajaraman, Sivaramakrishnan Hsu, Li-Yueh Sachdev, Vandana Antani, Sameer Med Image Anal Article Deep learning has a huge potential to transform echocardiography in clinical practice and point of care ultrasound testing by providing real-time analysis of cardiac structure and function. Automated echocardiography analysis is benefited through use of machine learning for tasks such as image quality assessment, view classification, cardiac region segmentation, and quantification of diagnostic indices. By taking advantage of high-performing deep neural networks, we propose a novel and eicient real-time system for echocardiography analysis and quantification. Our system uses a self-supervised modality-specific representation trained using a publicly available large-scale dataset. The trained representation is used to enhance the learning of target echo tasks with relatively small datasets. We also present a novel Trilateral Attention Network (TaNet) for real-time cardiac region segmentation. The proposed network uses a module for region localization and three lightweight pathways for encoding rich low-level, textural, and high-level features. Feature embeddings from these individual pathways are then aggregated for cardiac region segmentation. This network is fine-tuned using a joint loss function and training strategy. We extensively evaluate the proposed system and its components, which are echo view retrieval, cardiac segmentation, and quantification, using four echocardiography datasets. Our experimental results show a consistent improvement in the performance of echocardiography analysis tasks with enhanced computational eiciency that charts a path toward its adoption in clinical practice. Specifically, our results show superior real-time performance in retrieving good quality echo from individual cardiac view, segmenting cardiac chambers with complex overlaps, and extracting cardiac indices that highly agree with the experts’ values. The source code of our implementation can be found in the project ‘ s GitHub page. 2022-08 2022-06-09 /pmc/articles/PMC9310146/ /pubmed/35868819 http://dx.doi.org/10.1016/j.media.2022.102438 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Article
Zamzmi, Ghada
Rajaraman, Sivaramakrishnan
Hsu, Li-Yueh
Sachdev, Vandana
Antani, Sameer
Real-time echocardiography image analysis and quantification of cardiac indices
title Real-time echocardiography image analysis and quantification of cardiac indices
title_full Real-time echocardiography image analysis and quantification of cardiac indices
title_fullStr Real-time echocardiography image analysis and quantification of cardiac indices
title_full_unstemmed Real-time echocardiography image analysis and quantification of cardiac indices
title_short Real-time echocardiography image analysis and quantification of cardiac indices
title_sort real-time echocardiography image analysis and quantification of cardiac indices
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310146/
https://www.ncbi.nlm.nih.gov/pubmed/35868819
http://dx.doi.org/10.1016/j.media.2022.102438
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