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Cytoplasmic Injection of Zygotes to Genome Edit Naturally Occurring Sequence Variants Into Bovine Embryos

Genome editing provides opportunities to improve current cattle breeding strategies through targeted introduction of natural sequence variants, accelerating genetic gain. This can be achieved by harnessing homology-directed repair mechanisms following editor-induced cleavage of the genome in the pre...

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Detalles Bibliográficos
Autores principales: Wei, Jingwei, Brophy, Brigid, Cole, Sally-Ann, Moormann, Jannis, Boch, Jens, Laible, Gӧtz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310181/
https://www.ncbi.nlm.nih.gov/pubmed/35899192
http://dx.doi.org/10.3389/fgene.2022.925913

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