Oral dextran sulfate sodium administration induces peripheral spondyloarthritis features in SKG mice accompanied by intestinal bacterial translocation and systemic Th1 and Th17 cell activation

BACKGROUND: Spondyloarthritis (SpA) is an autoimmune and autoinflammatory musculoskeletal disease characterised by systemic enthesitis. Recent research has focused on subclinical inflammatory bowel disease (IBD) in SpA pathogenesis. SKG mice, harbouring the Zap70 W163C mutation, increase autoreactiv...

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Detalles Bibliográficos
Autores principales: Tabuchi, Yuya, Katsushima, Masao, Nishida, Yuri, Shirakashi, Mirei, Tsuji, Hideaki, Onizawa, Hideo, Kitagori, Koji, Akizuki, Shuji, Nakashima, Ran, Murakami, Kosaku, Murata, Koichi, Yoshifuji, Hajime, Tanaka, Masao, Morinobu, Akio, Hashimoto, Motomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310491/
https://www.ncbi.nlm.nih.gov/pubmed/35879738
http://dx.doi.org/10.1186/s13075-022-02844-4

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