Hepatocellular carcinoma chemoprevention by targeting the angiotensin-converting enzyme and EGFR transactivation

Hepatocellular carcinoma (HCC) is a leading cause of death among cirrhotic patients, for which chemopreventive strategies are lacking. Recently, we developed a simple human cell-based system modeling a clinical prognostic liver signature (PLS) predicting liver disease progression and HCC risk. In a...

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Detalles Bibliográficos
Autores principales: Crouchet, Emilie, Li, Shen, Sojoodi, Mozhdeh, Bandiera, Simonetta, Fujiwara, Naoto, El Saghire, Hussein, Zhu, Shijia, Qian, Tongqi, Rasha, Fahmida Akter, Del Zompo, Fabio, Barrett, Stephen C., Schaeffer, Eugénie, Oudot, Marine A., Ponsolles, Clara, Durand, Sarah C., Ghoshal, Sarani, Arora, Gunisha, Giannone, Fabio, Chung, Raymond T., Slovic, Nevena, Van Renne, Nicolaas, Felli, Emanuele, Pessaux, Patrick, Lupberger, Joachim, Pochet, Nathalie, Schuster, Catherine, Tanabe, Kenneth K., Hoshida, Yujin, Fuchs, Bryan C., Baumert, Thomas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310532/
https://www.ncbi.nlm.nih.gov/pubmed/35801591
http://dx.doi.org/10.1172/jci.insight.159254

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