Interventional hepatic apoC-III knockdown improves atherosclerotic plaque stability and remodeling by triglyceride lowering

Apolipoprotein C-III (apoC-III) is a critical regulator of triglyceride metabolism and correlates positively with hypertriglyceridemia and cardiovascular disease (CVD). It remains unclear if therapeutic apoC-III lowering reduces CVD risk and if the CVD correlation depends on the lipid-lowering or an...

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Detalles Bibliográficos
Autores principales: Ramms, Bastian, Patel, Sohan, Sun, Xiaoli, Pessentheiner, Ariane R., Ducasa, G. Michelle, Mullick, Adam E., Lee, Richard G., Crooke, Rosanne M., Tsimikas, Sotirios, Witztum, Joseph L., Gordts, Philip L.S.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310539/
https://www.ncbi.nlm.nih.gov/pubmed/35653195
http://dx.doi.org/10.1172/jci.insight.158414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310539/
https://www.ncbi.nlm.nih.gov/pubmed/35653195
http://dx.doi.org/10.1172/jci.insight.158414

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