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Integrated molecular profiling of patient‐derived ovarian cancer models identifies clinically relevant signatures and tumor vulnerabilities

High‐grade serous ovarian carcinoma (HGSOC) is a highly aggressive and intractable neoplasm, mainly because of its rapid dissemination into the abdominal cavity, a process that is favored by tumor‐associated peritoneal ascites. The precise molecular alterations involved in HGSOC onset and progressio...

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Detalles Bibliográficos
Autores principales: Lupia, Michela, Melocchi, Valentina, Bizzaro, Francesca, Lo Riso, Pietro, Dama, Elisa, Baronio, Micol, Ranghiero, Alberto, Barberis, Massimo, Bernard, Loris, Bertalot, Giovanni, Giavazzi, Raffaella, Testa, Giuseppe, Bianchi, Fabrizio, Cavallaro, Ugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310611/
https://www.ncbi.nlm.nih.gov/pubmed/35218560
http://dx.doi.org/10.1002/ijc.33983