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Patient and physician perspectives on alopecia areata: A real‐world assessment of severity and burden in Japan

The criteria used by physicians to assess alopecia areata severity and its associated burden from the patients' point of view are not well understood. We aimed to understand physician‐assessed determinants of disease severity, factors associated with severity, patient–physician concordance, and...

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Autores principales: Edson‐Heredia, Emily, Aranishi, Toshihiko, Isaka, Yoshitaka, Anderson, Peter, Marwaha, Simran, Piercy, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310764/
https://www.ncbi.nlm.nih.gov/pubmed/35343611
http://dx.doi.org/10.1111/1346-8138.16360
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author Edson‐Heredia, Emily
Aranishi, Toshihiko
Isaka, Yoshitaka
Anderson, Peter
Marwaha, Simran
Piercy, James
author_facet Edson‐Heredia, Emily
Aranishi, Toshihiko
Isaka, Yoshitaka
Anderson, Peter
Marwaha, Simran
Piercy, James
author_sort Edson‐Heredia, Emily
collection PubMed
description The criteria used by physicians to assess alopecia areata severity and its associated burden from the patients' point of view are not well understood. We aimed to understand physician‐assessed determinants of disease severity, factors associated with severity, patient–physician concordance, and patient‐reported burden by severity. Data were drawn from the Adelphi Alopecia Areata Disease Specific Programme™, a point‐in‐time survey of dermatologists and their alopecia areata patients in real‐world practice in Japan conducted between January and March 2021. Patients were categorized into three groups by current disease severity according to physician subjective assessment: mild, moderate, or severe. Demographics, clinical characteristics, and outcomes were described within and compared between the three patient groups. Our study of 97 dermatologists and 587 patients found overall scalp hair loss was the most important factor considered by physicians in determining disease severity. More severe disease was associated with loss of eyebrow hair, eyelashes, and hair loss from other body areas. Agreement on disease severity between physicians and patients was moderate. From the patient perspective, greater severity of alopecia areata was associated with greater anxiety and depression, with lower work productivity and worse quality of life. Our study provides insights into which factors physicians use to determine alopecia areata severity, how physician and patient severity assessments compare, and the burden of alopecia areata on patients.
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spelling pubmed-93107642022-07-29 Patient and physician perspectives on alopecia areata: A real‐world assessment of severity and burden in Japan Edson‐Heredia, Emily Aranishi, Toshihiko Isaka, Yoshitaka Anderson, Peter Marwaha, Simran Piercy, James J Dermatol Original Articles The criteria used by physicians to assess alopecia areata severity and its associated burden from the patients' point of view are not well understood. We aimed to understand physician‐assessed determinants of disease severity, factors associated with severity, patient–physician concordance, and patient‐reported burden by severity. Data were drawn from the Adelphi Alopecia Areata Disease Specific Programme™, a point‐in‐time survey of dermatologists and their alopecia areata patients in real‐world practice in Japan conducted between January and March 2021. Patients were categorized into three groups by current disease severity according to physician subjective assessment: mild, moderate, or severe. Demographics, clinical characteristics, and outcomes were described within and compared between the three patient groups. Our study of 97 dermatologists and 587 patients found overall scalp hair loss was the most important factor considered by physicians in determining disease severity. More severe disease was associated with loss of eyebrow hair, eyelashes, and hair loss from other body areas. Agreement on disease severity between physicians and patients was moderate. From the patient perspective, greater severity of alopecia areata was associated with greater anxiety and depression, with lower work productivity and worse quality of life. Our study provides insights into which factors physicians use to determine alopecia areata severity, how physician and patient severity assessments compare, and the burden of alopecia areata on patients. John Wiley and Sons Inc. 2022-03-28 2022-06 /pmc/articles/PMC9310764/ /pubmed/35343611 http://dx.doi.org/10.1111/1346-8138.16360 Text en © 2022 Eli Lilly and Company and Adelphi. The Journal of Dermatology published by John Wiley & Sons Australia, Ltd on behalf of Japanese Dermatological Association. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Edson‐Heredia, Emily
Aranishi, Toshihiko
Isaka, Yoshitaka
Anderson, Peter
Marwaha, Simran
Piercy, James
Patient and physician perspectives on alopecia areata: A real‐world assessment of severity and burden in Japan
title Patient and physician perspectives on alopecia areata: A real‐world assessment of severity and burden in Japan
title_full Patient and physician perspectives on alopecia areata: A real‐world assessment of severity and burden in Japan
title_fullStr Patient and physician perspectives on alopecia areata: A real‐world assessment of severity and burden in Japan
title_full_unstemmed Patient and physician perspectives on alopecia areata: A real‐world assessment of severity and burden in Japan
title_short Patient and physician perspectives on alopecia areata: A real‐world assessment of severity and burden in Japan
title_sort patient and physician perspectives on alopecia areata: a real‐world assessment of severity and burden in japan
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310764/
https://www.ncbi.nlm.nih.gov/pubmed/35343611
http://dx.doi.org/10.1111/1346-8138.16360
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