Drug Disposition Protein Quantification in Matched Human Jejunum and Liver From Donors With Obesity

Mathematical models, such as physiologically‐based pharmacokinetic models, are used to predict, for example, drug disposition and toxicity. However, populations differ in the abundance of proteins involved in these processes. To improve the building and refinement of such models, they must take into...

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Detalles Bibliográficos
Autores principales: Wegler, Christine, Wiśniewski, Jacek R., Robertsen, Ida, Christensen, Hege, Kristoffer Hertel, Jens, Hjelmesæth, Jøran, Jansson‐Löfmark, Rasmus, Åsberg, Anders, Andersson, Tommy B., Artursson, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310776/
https://www.ncbi.nlm.nih.gov/pubmed/35158408
http://dx.doi.org/10.1002/cpt.2558

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