Cargando…
Preparation of uniform-sized GeXIVA[1,2]-loaded PLGA microspheres as long-effective release system with high encapsulation efficiency
The purpose of this study was to prepare GeXIVA[1,2] PLGA microspheres by W/O/W re-emulsification-solvent evaporation technology and to develop sustained-release formulations to meet the clinical treatment needs of chronic neuropathic pain. Through prescription optimization, the uniformity of partic...
Autores principales: | Li, Lu, Li, Zhiguo, Guo, Yongxin, Zhang, Kai, Mi, Weidong, Liu, Jing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310807/ https://www.ncbi.nlm.nih.gov/pubmed/35866254 http://dx.doi.org/10.1080/10717544.2022.2089297 |
Ejemplares similares
-
Novel αO-conotoxin GeXIVA[1,2] Nonaddictive Analgesic with Pharmacokinetic Modelling-Based Mechanistic Assessment
por: Zhu, Xiaoyu, et al.
Publicado: (2022) -
Lyophilization Serves as an Effective Strategy for Drug Development of the α9α10 Nicotinic Acetylcholine Receptor Antagonist α-Conotoxin GeXIVA[1,2]
por: Li, Zhiguo, et al.
Publicado: (2021) -
Differential Expression of Nicotine Acetylcholine Receptors Associates with Human Breast Cancer and Mediates Antitumor Activity of αO-Conotoxin GeXIVA
por: Sun, Zhihua, et al.
Publicado: (2020) -
αO-Conotoxin GeXIVA Inhibits the Growth of Breast Cancer Cells via Interaction with α9 Nicotine Acetylcholine Receptors
por: Sun, Zhihua, et al.
Publicado: (2020) -
The α9α10 Nicotinic Acetylcholine Receptor Antagonist αO-Conotoxin GeXIVA[1,2] Alleviates and Reverses Chemotherapy-Induced Neuropathic Pain
por: Wang, Huanbai, et al.
Publicado: (2019)