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MS‐Driven Metabolic Alterations Are Recapitulated in iPSC‐Derived Astrocytes
OBJECTIVE: Astrocytes play a significant role in the pathology of multiple sclerosis (MS). Nevertheless, for ethical reasons, most studies in these cells were performed using the Experimental Autoimmune Encephalomyelitis model. As there are significant differences between human and mouse cells, we a...
Autores principales: | Ghirotto, Bruno, Oliveira, Danyllo F., Cipelli, Marcella, Basso, Paulo J., de Lima, Jean, Breda, Cristiane N. S., Ribeiro, Henrique C., Silva, Camille C. C., Sertié, Andrea L., Oliveira, Antonio Edson R., Hiyane, Meire I., Caldini, Elia G., Sussulini, Alessandra, Nakaya, Helder I., Kowaltowski, Alicia J., Oliveira, Enedina M. L., Zatz, Mayana, Câmara, Niels O. S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9310856/ https://www.ncbi.nlm.nih.gov/pubmed/35226368 http://dx.doi.org/10.1002/ana.26336 |
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