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Time trends in psychotropic drug prescriptions in Dutch nursing home residents with dementia between 2003 and 2018
OBJECTIVE: Several European studies investigated the trends in psychotropic drug prescriptions (PDPs) among nursing home (NH) residents and reported a decline in antipsychotics prescriptions. Since the Dutch long‐term care system differs from other European systems (e.g. higher threshold for NH admi...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311063/ https://www.ncbi.nlm.nih.gov/pubmed/35297551 http://dx.doi.org/10.1002/gps.5697 |
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author | Du, Jiamin Janus, Sarah Voorthuis, Brenda van Manen, Jeannette Achterberg, Wilco Smalbrugge, Martin Zwijsen, Sandra Gerritsen, Debby Koopmans, Raymond Zuidema, Sytse |
author_facet | Du, Jiamin Janus, Sarah Voorthuis, Brenda van Manen, Jeannette Achterberg, Wilco Smalbrugge, Martin Zwijsen, Sandra Gerritsen, Debby Koopmans, Raymond Zuidema, Sytse |
author_sort | Du, Jiamin |
collection | PubMed |
description | OBJECTIVE: Several European studies investigated the trends in psychotropic drug prescriptions (PDPs) among nursing home (NH) residents and reported a decline in antipsychotics prescriptions. Since the Dutch long‐term care system differs from other European systems (e.g. higher threshold for NH admission and trained elderly care physicians), this study explores the trends in PDPs in Dutch NH residents with dementia. METHODS: The study used data from nine studies, comprising two cross‐sectional studies, one cohort study, and six cluster‐randomized controlled trials, collected in Dutch NHs between 2003 and 2018. With multilevel logistic regression analysis, NHs as a random effect, we estimated the trends in PDPs overall and for five specific psychotropic drug groups (antipsychotics, antidepressants, anxiolytics, hypnotics, and anti‐dementia drugs), adjusting for confounders: age, gender, severity of dementia, severity of neuropsychiatric symptoms, and length of stay in NHs. RESULTS: The absolute prescription rate of antipsychotics was 37.5% in 2003 and decreased (OR = 0.947, 95% CI [0.926, 0.970]) every year. The absolute prescription rate of anti‐dementia drugs was 0.8% in 2003 and increased (OR = 1.162, 95% CI [1.105, 1.223]) per year. The absolute rate of overall PDPs declined from 62.7% in 2003 to 40.4% in 2018. CONCLUSIONS: Among Dutch NH residents with dementia, the odds of antipsychotics prescriptions decreased by 5.3% per year while the odds of anti‐dementia drug prescriptions increased by 16.2%. There were no distinct trends in antidepressants, anxiolytics, and hypnotics prescriptions. However, overall PDPs were still high. The PDPs in NH residents remain an issue of concern. |
format | Online Article Text |
id | pubmed-9311063 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-93110632022-07-29 Time trends in psychotropic drug prescriptions in Dutch nursing home residents with dementia between 2003 and 2018 Du, Jiamin Janus, Sarah Voorthuis, Brenda van Manen, Jeannette Achterberg, Wilco Smalbrugge, Martin Zwijsen, Sandra Gerritsen, Debby Koopmans, Raymond Zuidema, Sytse Int J Geriatr Psychiatry Research Article OBJECTIVE: Several European studies investigated the trends in psychotropic drug prescriptions (PDPs) among nursing home (NH) residents and reported a decline in antipsychotics prescriptions. Since the Dutch long‐term care system differs from other European systems (e.g. higher threshold for NH admission and trained elderly care physicians), this study explores the trends in PDPs in Dutch NH residents with dementia. METHODS: The study used data from nine studies, comprising two cross‐sectional studies, one cohort study, and six cluster‐randomized controlled trials, collected in Dutch NHs between 2003 and 2018. With multilevel logistic regression analysis, NHs as a random effect, we estimated the trends in PDPs overall and for five specific psychotropic drug groups (antipsychotics, antidepressants, anxiolytics, hypnotics, and anti‐dementia drugs), adjusting for confounders: age, gender, severity of dementia, severity of neuropsychiatric symptoms, and length of stay in NHs. RESULTS: The absolute prescription rate of antipsychotics was 37.5% in 2003 and decreased (OR = 0.947, 95% CI [0.926, 0.970]) every year. The absolute prescription rate of anti‐dementia drugs was 0.8% in 2003 and increased (OR = 1.162, 95% CI [1.105, 1.223]) per year. The absolute rate of overall PDPs declined from 62.7% in 2003 to 40.4% in 2018. CONCLUSIONS: Among Dutch NH residents with dementia, the odds of antipsychotics prescriptions decreased by 5.3% per year while the odds of anti‐dementia drug prescriptions increased by 16.2%. There were no distinct trends in antidepressants, anxiolytics, and hypnotics prescriptions. However, overall PDPs were still high. The PDPs in NH residents remain an issue of concern. John Wiley and Sons Inc. 2022-03-17 2022-04 /pmc/articles/PMC9311063/ /pubmed/35297551 http://dx.doi.org/10.1002/gps.5697 Text en © 2022 The Authors. International Journal of Geriatric Psychiatry published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Research Article Du, Jiamin Janus, Sarah Voorthuis, Brenda van Manen, Jeannette Achterberg, Wilco Smalbrugge, Martin Zwijsen, Sandra Gerritsen, Debby Koopmans, Raymond Zuidema, Sytse Time trends in psychotropic drug prescriptions in Dutch nursing home residents with dementia between 2003 and 2018 |
title | Time trends in psychotropic drug prescriptions in Dutch nursing home residents with dementia between 2003 and 2018 |
title_full | Time trends in psychotropic drug prescriptions in Dutch nursing home residents with dementia between 2003 and 2018 |
title_fullStr | Time trends in psychotropic drug prescriptions in Dutch nursing home residents with dementia between 2003 and 2018 |
title_full_unstemmed | Time trends in psychotropic drug prescriptions in Dutch nursing home residents with dementia between 2003 and 2018 |
title_short | Time trends in psychotropic drug prescriptions in Dutch nursing home residents with dementia between 2003 and 2018 |
title_sort | time trends in psychotropic drug prescriptions in dutch nursing home residents with dementia between 2003 and 2018 |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311063/ https://www.ncbi.nlm.nih.gov/pubmed/35297551 http://dx.doi.org/10.1002/gps.5697 |
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