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Comparison of the clinical frailty score (CFS) to the National Emergency Laparotomy Audit (NELA) risk calculator in all patients undergoing emergency laparotomy

AIM: There is evolving evidence that preoperative frailty predicts outcomes of older adults undergoing emergency laparotomy (EmLap). We assessed frailty scoring in an emergency surgical population that included patients of all ages and then compared this to an established perioperative prognostic sc...

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Autores principales: Palaniappan, Subbra, Soiza, Roy L., Duffy, Siobhan, Moug, Susan J., Myint, Phyo Kyaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311201/
https://www.ncbi.nlm.nih.gov/pubmed/35167177
http://dx.doi.org/10.1111/codi.16089
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author Palaniappan, Subbra
Soiza, Roy L.
Duffy, Siobhan
Moug, Susan J.
Myint, Phyo Kyaw
author_facet Palaniappan, Subbra
Soiza, Roy L.
Duffy, Siobhan
Moug, Susan J.
Myint, Phyo Kyaw
author_sort Palaniappan, Subbra
collection PubMed
description AIM: There is evolving evidence that preoperative frailty predicts outcomes of older adults undergoing emergency laparotomy (EmLap). We assessed frailty scoring in an emergency surgical population that included patients of all ages and then compared this to an established perioperative prognostic score. METHOD: Data from the prospective Emergency Laparoscopic and Laparotomy Scottish Audit (ELLSA; November 2017–October 2018) was used. All adults over 18 were included. Frailty was measured using 7‐point clinical frailty score (CFS). Outcome measures: 30‐day mortality, hospital length of stay (LOS), 30‐day readmission. Areas under the receiver‐operating characteristic (ROC) curves were calculated for CFS (1–7) and compared to the National Emergency Laparotomy Audit (NELA) score with Forest plots used to compare 30‐day mortality across CFS and NELA categories. RESULTS: A total of 2246 patients (median age 65 years [IQR 51–75]; female 51%) underwent EmLap (60% for colorectal pathology). A total of 10.6% were frail preoperatively (≥CFS 5). As CFS increased so did 30‐day mortality (2.1% CFS1 to 25.3% CFS6 and 7; ꭓ (2)78.2, p < 0.001) and median LOS (10 days CFS1 to 20 days CFS6 and 7; p < 0.001). Readmission rates did not differ significantly across CFS. ROC (95% CI) for mortality was 0.71 (0.65–0.77) for CFS and 0.84 (0.78–0.89) for NELA. Addition of CFS to NELA did not increase ROC value. CONCLUSION: This study supports the prognostic role of frailty in the emergency surgical setting, finding increasing frailty to be associated with increased mortality and longer LOS in adults of all ages. Although NELA performed better, CFS remained predictive and has the advantage of being calculated preoperatively to aid decision‐making and treatment planning.
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spelling pubmed-93112012022-07-29 Comparison of the clinical frailty score (CFS) to the National Emergency Laparotomy Audit (NELA) risk calculator in all patients undergoing emergency laparotomy Palaniappan, Subbra Soiza, Roy L. Duffy, Siobhan Moug, Susan J. Myint, Phyo Kyaw Colorectal Dis Original Articles AIM: There is evolving evidence that preoperative frailty predicts outcomes of older adults undergoing emergency laparotomy (EmLap). We assessed frailty scoring in an emergency surgical population that included patients of all ages and then compared this to an established perioperative prognostic score. METHOD: Data from the prospective Emergency Laparoscopic and Laparotomy Scottish Audit (ELLSA; November 2017–October 2018) was used. All adults over 18 were included. Frailty was measured using 7‐point clinical frailty score (CFS). Outcome measures: 30‐day mortality, hospital length of stay (LOS), 30‐day readmission. Areas under the receiver‐operating characteristic (ROC) curves were calculated for CFS (1–7) and compared to the National Emergency Laparotomy Audit (NELA) score with Forest plots used to compare 30‐day mortality across CFS and NELA categories. RESULTS: A total of 2246 patients (median age 65 years [IQR 51–75]; female 51%) underwent EmLap (60% for colorectal pathology). A total of 10.6% were frail preoperatively (≥CFS 5). As CFS increased so did 30‐day mortality (2.1% CFS1 to 25.3% CFS6 and 7; ꭓ (2)78.2, p < 0.001) and median LOS (10 days CFS1 to 20 days CFS6 and 7; p < 0.001). Readmission rates did not differ significantly across CFS. ROC (95% CI) for mortality was 0.71 (0.65–0.77) for CFS and 0.84 (0.78–0.89) for NELA. Addition of CFS to NELA did not increase ROC value. CONCLUSION: This study supports the prognostic role of frailty in the emergency surgical setting, finding increasing frailty to be associated with increased mortality and longer LOS in adults of all ages. Although NELA performed better, CFS remained predictive and has the advantage of being calculated preoperatively to aid decision‐making and treatment planning. John Wiley and Sons Inc. 2022-03-15 2022-06 /pmc/articles/PMC9311201/ /pubmed/35167177 http://dx.doi.org/10.1111/codi.16089 Text en © 2022 The Authors. Colorectal Disease published by John Wiley & Sons Ltd on behalf of Association of Coloproctology of Great Britain and Ireland. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Palaniappan, Subbra
Soiza, Roy L.
Duffy, Siobhan
Moug, Susan J.
Myint, Phyo Kyaw
Comparison of the clinical frailty score (CFS) to the National Emergency Laparotomy Audit (NELA) risk calculator in all patients undergoing emergency laparotomy
title Comparison of the clinical frailty score (CFS) to the National Emergency Laparotomy Audit (NELA) risk calculator in all patients undergoing emergency laparotomy
title_full Comparison of the clinical frailty score (CFS) to the National Emergency Laparotomy Audit (NELA) risk calculator in all patients undergoing emergency laparotomy
title_fullStr Comparison of the clinical frailty score (CFS) to the National Emergency Laparotomy Audit (NELA) risk calculator in all patients undergoing emergency laparotomy
title_full_unstemmed Comparison of the clinical frailty score (CFS) to the National Emergency Laparotomy Audit (NELA) risk calculator in all patients undergoing emergency laparotomy
title_short Comparison of the clinical frailty score (CFS) to the National Emergency Laparotomy Audit (NELA) risk calculator in all patients undergoing emergency laparotomy
title_sort comparison of the clinical frailty score (cfs) to the national emergency laparotomy audit (nela) risk calculator in all patients undergoing emergency laparotomy
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311201/
https://www.ncbi.nlm.nih.gov/pubmed/35167177
http://dx.doi.org/10.1111/codi.16089
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