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Computational Design, Synthesis, and Photochemistry of Cy7‐PPG, an Efficient NIR‐Activated Photolabile Protecting Group for Therapeutic Applications

Photolabile Protecting Groups (PPGs) are molecular tools used, for example, in photopharmacology for the activation of drugs with light, enabling spatiotemporal control over their potency. Yet, red‐shifting of PPG activation wavelengths into the NIR range, which penetrates the deepest in tissue, has...

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Detalles Bibliográficos
Autores principales: Alachouzos, Georgios, Schulte, Albert M., Mondal, Anirban, Szymanski, Wiktor, Feringa, Ben L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311213/
https://www.ncbi.nlm.nih.gov/pubmed/35181979
http://dx.doi.org/10.1002/anie.202201308