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Influence of Socio-Demographic Factors in Patients With Cutaneous Lupus Erythematosus
Cutaneous lupus erythematosus (CLE) is a chronic autoimmune skin disease with potential for systemic involvement, disfigurement, and significant disease burden. The relationships of demographics and socioeconomic status with patients with CLE are emerging topics with important clinical implications....
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311297/ https://www.ncbi.nlm.nih.gov/pubmed/35899206 http://dx.doi.org/10.3389/fmed.2022.916134 |
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author | Walker, Amanda M. Lu, Grace Clifton, Shari C. Ogunsanya, Motolani E. Chong, Benjamin F. |
author_facet | Walker, Amanda M. Lu, Grace Clifton, Shari C. Ogunsanya, Motolani E. Chong, Benjamin F. |
author_sort | Walker, Amanda M. |
collection | PubMed |
description | Cutaneous lupus erythematosus (CLE) is a chronic autoimmune skin disease with potential for systemic involvement, disfigurement, and significant disease burden. The relationships of demographics and socioeconomic status with patients with CLE are emerging topics with important clinical implications. The primary objective of our study is to perform a literature review of studies that have investigated demographic and socioeconomic factors amongst patients with CLE and determine whether these factors influence diagnosis frequency, disease severity and outcomes or health related quality of life. We searched multiple databases to identify literature addressing CLE and concepts such as race, ethnicity, gender, income, education level and geographic location. Information regarding primary research objective was extracted from all full text articles, and a summary of findings was prepared. We found that race and ethnicity can influence CLE diagnosis frequency and disease outcomes. Chronic cutaneous lupus (CCLE) occurs more frequently in Black patients, often with higher overall disease damage. Differences between genders exist in CLE in terms of health-related quality of life, as female gender was a risk factor for worse quality of life in several studies. Lower income, low educational attainment, and lack of health insurance all contribute to poorer overall outcomes in CLE patients. This review will help inform physicians about populations at risk for potentially worse outcomes to guide treatment decisions for patients with CLE and provide important information to design interventions that address modifiable social determinants of health in this population. |
format | Online Article Text |
id | pubmed-9311297 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-93112972022-07-26 Influence of Socio-Demographic Factors in Patients With Cutaneous Lupus Erythematosus Walker, Amanda M. Lu, Grace Clifton, Shari C. Ogunsanya, Motolani E. Chong, Benjamin F. Front Med (Lausanne) Medicine Cutaneous lupus erythematosus (CLE) is a chronic autoimmune skin disease with potential for systemic involvement, disfigurement, and significant disease burden. The relationships of demographics and socioeconomic status with patients with CLE are emerging topics with important clinical implications. The primary objective of our study is to perform a literature review of studies that have investigated demographic and socioeconomic factors amongst patients with CLE and determine whether these factors influence diagnosis frequency, disease severity and outcomes or health related quality of life. We searched multiple databases to identify literature addressing CLE and concepts such as race, ethnicity, gender, income, education level and geographic location. Information regarding primary research objective was extracted from all full text articles, and a summary of findings was prepared. We found that race and ethnicity can influence CLE diagnosis frequency and disease outcomes. Chronic cutaneous lupus (CCLE) occurs more frequently in Black patients, often with higher overall disease damage. Differences between genders exist in CLE in terms of health-related quality of life, as female gender was a risk factor for worse quality of life in several studies. Lower income, low educational attainment, and lack of health insurance all contribute to poorer overall outcomes in CLE patients. This review will help inform physicians about populations at risk for potentially worse outcomes to guide treatment decisions for patients with CLE and provide important information to design interventions that address modifiable social determinants of health in this population. Frontiers Media S.A. 2022-07-11 /pmc/articles/PMC9311297/ /pubmed/35899206 http://dx.doi.org/10.3389/fmed.2022.916134 Text en Copyright © 2022 Walker, Lu, Clifton, Ogunsanya and Chong. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Medicine Walker, Amanda M. Lu, Grace Clifton, Shari C. Ogunsanya, Motolani E. Chong, Benjamin F. Influence of Socio-Demographic Factors in Patients With Cutaneous Lupus Erythematosus |
title | Influence of Socio-Demographic Factors in Patients With Cutaneous Lupus Erythematosus |
title_full | Influence of Socio-Demographic Factors in Patients With Cutaneous Lupus Erythematosus |
title_fullStr | Influence of Socio-Demographic Factors in Patients With Cutaneous Lupus Erythematosus |
title_full_unstemmed | Influence of Socio-Demographic Factors in Patients With Cutaneous Lupus Erythematosus |
title_short | Influence of Socio-Demographic Factors in Patients With Cutaneous Lupus Erythematosus |
title_sort | influence of socio-demographic factors in patients with cutaneous lupus erythematosus |
topic | Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311297/ https://www.ncbi.nlm.nih.gov/pubmed/35899206 http://dx.doi.org/10.3389/fmed.2022.916134 |
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