Cargando…
Peripheral gene signatures reveal distinct cancer patient immunotypes with therapeutic implications for autologous DC-based vaccines
Dendritic cells (DCs) have received considerable attention as potential targets for the development of novel cancer immunotherapies. However, the clinical efficacy of DC-based vaccines remains suboptimal, largely reflecting local and systemic immunosuppression at baseline. An autologous DC-based vac...
Autores principales: | Hensler, Michal, Rakova, Jana, Kasikova, Lenka, Lanickova, Tereza, Pasulka, Josef, Holicek, Peter, Hraska, Marek, Hrnciarova, Tereza, Kadlecova, Pavla, Schoenenberger, Andreu, Sochorova, Klara, Rozkova, Daniela, Sojka, Ludek, Drozenova, Jana, Laco, Jan, Horvath, Rudolf, Podrazil, Michal, Hongyan, Guo, Brtnicky, Tomas, Halaska, Michal J., Rob, Lukas, Ryska, Ales, Coosemans, An, Vergote, Ignace, Garg, Abhishek D., Cibula, David, Bartunkova, Jirina, Spisek, Radek, Fucikova, Jitka |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311316/ https://www.ncbi.nlm.nih.gov/pubmed/35898703 http://dx.doi.org/10.1080/2162402X.2022.2101596 |
Ejemplares similares
-
TIM-3 levels correlate with enhanced NK cell cytotoxicity and improved clinical outcome in AML patients
por: Rakova, Jana, et al.
Publicado: (2021) -
M2-like macrophages dictate clinically relevant immunosuppression in metastatic ovarian cancer
por: Hensler, Michal, et al.
Publicado: (2020) -
Expression of tumor antigens on primary ovarian cancer cells compared to established ovarian cancer cell lines
por: Kloudová, Kamila, et al.
Publicado: (2016) -
Calreticulin exposure correlates with robust adaptive antitumor immunity and favorable prognosis in ovarian carcinoma patients
por: Kasikova, Lenka, et al.
Publicado: (2019) -
Type I interferon signaling in malignant blasts contributes to treatment efficacy in AML patients
por: Holicek, Peter, et al.
Publicado: (2023)