Cargando…

Principles and correction of 5’-splice site selection

In Eukarya, immature mRNA transcripts (pre-mRNA) often contain coding sequences, or exons, interleaved by non-coding sequences, or introns. Introns are removed upon splicing, and further regulation of the retained exons leads to alternatively spliced mRNA. The splicing reaction requires the stepwise...

Descripción completa

Detalles Bibliográficos
Autores principales:	Malard, Florian, Mackereth, Cameron D, Campagne, Sébastien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311317/ https://www.ncbi.nlm.nih.gov/pubmed/35866748 http://dx.doi.org/10.1080/15476286.2022.2100971

Ejemplares similares

Splicing factor SUP-12 and the molecular complexity of apparent cooperativity
por: Mackereth, Cameron D
Publicado: (2015)

Molecular basis of RNA-binding and autoregulation by the cancer-associated splicing factor RBM39
por: Campagne, Sébastien, et al.
Publicado: (2023)

Structural basis of UCUU RNA motif recognition by splicing factor RBM20
por: Upadhyay, Santosh Kumar, et al.
Publicado: (2020)

Modulation of 5' splice site selection using tailed oligonucleotides carrying splicing signals
por: Gendron, Daniel, et al.
Publicado: (2006)

Noncanonical registers and base pairs in human 5′ splice-site selection
por: Tan, Jiazi, et al.
Publicado: (2016)

Oriented Scanning Is the Leading Mechanism Underlying 5′ Splice Site Selection in Mammals
por: Borensztajn, Keren, et al.
Publicado: (2006)

Functional analysis of Cwc24 ZF-domain in 5′ splice site selection
por: Wu, Nan-Ying, et al.
Publicado: (2019)

Identification of alternative 5′/3′ splice sites based on the mechanism of splice site competition
por: Xia, Huiyu, et al.
Publicado: (2006)

Regulation of 3′ splice site selection after step 1 of splicing by spliceosomal C* proteins
por: Dybkov, Olexandr, et al.
Publicado: (2023)

Recurrent Spliceosome Mutations in Cancer: Mechanisms and Consequences of Aberrant Splice Site Selection
por: Niño, Carlos A., et al.
Publicado: (2022)

Splicing proofreading at 5′ splice sites by ATPase Prp28p
por: Yang, Fei, et al.
Publicado: (2013)

A Quality Control Mechanism of Splice Site Selection Abrogated under Stress and in Cancer
por: Arafat, Maram, et al.
Publicado: (2022)

Exonic splice regulation imposes strong selection at synonymous sites
por: Savisaar, Rosina, et al.
Publicado: (2018)

A novel role for nucleolin in splice site selection
por: Shefer, Kinneret, et al.
Publicado: (2022)

Pathogenicity and selective constraint on variation near splice sites
por: Lord, Jenny, et al.
Publicado: (2019)

Alternative splicing at GYNNGY 5′ splice sites: more noise, less regulation
por: Wang, Meng, et al.
Publicado: (2014)

The Pivotal Roles of TIA Proteins in 5′ Splice-Site Selection of Alu Exons and Across Evolution
por: Gal-Mark, Nurit, et al.
Publicado: (2009)

Retroviral Integration Site Selection
por: Desfarges, Sébastien, et al.
Publicado: (2010)

Conserved binding of GCAC motifs by MEC-8, couch potato, and the RBPMS protein family
por: Soufari, Heddy, et al.
Publicado: (2017)

Molecular details of the CPSF73-CPSF100 C-terminal heterodimer and interaction with Symplekin
por: Thore, Stéphane, et al.
Publicado: (2023)

Activation of a cryptic 5′ splice site reverses the impact of pathogenic splice site mutations in the spinal muscular atrophy gene
por: Singh, Natalia N., et al.
Publicado: (2017)

Mouse nuclear RNAi-defective 2 promotes splicing of weak 5′ splice sites
por: Flemr, Matyas, et al.
Publicado: (2023)

Weak Negative and Positive Selection and the Drift Load at Splice Sites
por: Denisov, Stepan V., et al.
Publicado: (2014)

Yeast Prp2 liberates the 5′ splice site and the branch site adenosine for catalysis of pre-mRNA splicing
por: Bao, Penghui, et al.
Publicado: (2017)

Extended base pair complementarity between U1 snRNA and the 5′ splice site does not inhibit splicing in higher eukaryotes, but rather increases 5′ splice site recognition
por: Freund, Marcel, et al.
Publicado: (2005)

Histone H1.5 binds over splice sites in chromatin and regulates alternative splicing
por: Glaich, Ohad, et al.
Publicado: (2019)

An in vitro reconstituted U1 snRNP allows the study of the disordered regions of the particle and the interactions with proteins and ligands
por: Campagne, Sébastien, et al.
Publicado: (2021)

Design principles for site-selective hydroxylation by a Rieske oxygenase
por: Liu, Jianxin, et al.
Publicado: (2022)

Correction: Splice site identification using probabilistic parameters and SVM classification
por: Baten, AKMA, et al.
Publicado: (2007)

Stochastic principles governing alternative splicing of RNA
por: Hu, Jianfei, et al.
Publicado: (2017)

Genetic correction of splice site mutation in purified and enriched myoblasts isolated from mdx(5cv )mice
por: Maguire, Katie, et al.
Publicado: (2009)

Selection against tandem splice sites affecting structured protein regions
por: Hiller, Michael, et al.
Publicado: (2008)

Design principles for bifunctional targeted oligonucleotide enhancers of splicing
por: Owen, Nicholas, et al.
Publicado: (2011)

DBASS3 and DBASS5: databases of aberrant 3′- and 5′-splice sites
por: Buratti, Emanuele, et al.
Publicado: (2011)

In vitro and in silico analysis reveals an efficient algorithm to predict the splicing consequences of mutations at the 5′ splice sites
por: Sahashi, Kentaro, et al.
Publicado: (2007)

Sequencing of lariat termini in S. cerevisiae reveals 5′ splice sites, branch points, and novel splicing events
por: Qin, Daoming, et al.
Publicado: (2016)

Alternative splicing regulation at tandem 3′ splice sites
por: Akerman, Martin, et al.
Publicado: (2006)

SplicePort—An interactive splice-site analysis tool
por: Dogan, Rezarta Islamaj, et al.
Publicado: (2007)

Regulation of BCL-X splicing reveals a role for the polypyrimidine tract binding protein (PTBP1/hnRNP I) in alternative 5′ splice site selection
por: Bielli, Pamela, et al.
Publicado: (2014)

COSSMO: predicting competitive alternative splice site selection using deep learning
por: Bretschneider, Hannes, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_i9gcb5kbsfoatmulvl0v2t5b4q