STEMIN and YAP5SA synthetic modified mRNAs regenerate and repair infarcted mouse hearts

INTRODUCTION: The adult heart lacks the regenerative capacity to self-repair. Serum response factor (SRF) is essential for heart organogenesis, sarcomerogenesis, and contractility. SRF interacts with co-factors, such as NKX2.5 and GATA4, required for cardiac specified gene activity. ETS factors such...

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Detalles Bibliográficos
Autores principales: Xiao, Siyu, Liang, Rui, Lucero, Emilio, McConnell, Bradley K., Chen, Zhishi, Chang, Jiang, Navran, Stephen, Schwartz, Robert J., Iyer, Dinakar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311335/
https://www.ncbi.nlm.nih.gov/pubmed/35891703
http://dx.doi.org/10.20517/jca.2022.20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311335/
https://www.ncbi.nlm.nih.gov/pubmed/35891703
http://dx.doi.org/10.20517/jca.2022.20

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