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Strategies to Reduce the On‐Target Platelet Toxicity of Bcl‐x(L) Inhibitors: PROTACs, SNIPERs and Prodrug‐Based Approaches
Apoptosis is a highly regulated cellular process. Aberration in apoptosis is a common characteristic of various disorders. Therefore, proteins involved in apoptosis are prime targets in multiple therapies. Bcl‐x(L) is an antiapoptotic protein. Compared to other antiapoptotic proteins, the expression...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311450/ https://www.ncbi.nlm.nih.gov/pubmed/35263486 http://dx.doi.org/10.1002/cbic.202100689 |