Deciphering the Path of S-nitrosation of Human Thioredoxin: Evidence of an Internal NO Transfer and Implication for the Cellular Responses to NO

Nitric oxide (NO) is a free radical with a signaling capacity. Its cellular functions are achieved mainly through S-nitrosation where thioredoxin (hTrx) is pivotal in the S-transnitrosation to specific cellular targets. In this study, we use NMR spectroscopy and mass spectrometry to follow the mecha...

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Detalles Bibliográficos
Autores principales: Almeida, Vitor S., Miller, Lara L., Delia, João P. G., Magalhães, Augusto V., Caruso, Icaro P., Iqbal, Anwar, Almeida, Fabio C. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311519/
https://www.ncbi.nlm.nih.gov/pubmed/35883729
http://dx.doi.org/10.3390/antiox11071236

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