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Epoxomicin, a Selective Proteasome Inhibitor, Activates AIM2 Inflammasome in Human Retinal Pigment Epithelium Cells

Emerging evidence suggests that the intracellular clearance system plays a vital role in maintaining homeostasis and in regulating oxidative stress and inflammation in retinal pigment epithelium (RPE) cells. Dysfunctional proteasomes and autophagy in RPE cells have been associated with the pathogene...

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Detalles Bibliográficos
Autores principales:	Sridevi Gurubaran, Iswariyaraja, Hytti, Maria, Kaarniranta, Kai, Kauppinen, Anu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311580/ https://www.ncbi.nlm.nih.gov/pubmed/35883779 http://dx.doi.org/10.3390/antiox11071288

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