Genetic and observational evidence: No independent role for cholesterol efflux over static high‐density lipoprotein concentration measures in coronary heart disease risk assessment

BACKGROUND: Observational findings for high‐density lipoprotein (HDL)‐mediated cholesterol efflux capacity (HDL‐CEC) and coronary heart disease (CHD) appear inconsistent, and knowledge of the genetic architecture of HDL‐CEC is limited. OBJECTIVES: A large‐scale observational study on the association...

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Detalles Bibliográficos
Autores principales: Kuusisto, Sanna, Karjalainen, Minna K., Tillin, Therese, Kangas, Antti J., Holmes, Michael V., Kähönen, Mika, Lehtimäki, Terho, Viikari, Jorma, Perola, Markus, Chaturvedi, Nishi, Salomaa, Veikko, Raitakari, Olli T., Järvelin, Marjo‐Riitta, Kettunen, Johannes, Ala‐Korpela, Mika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311699/
https://www.ncbi.nlm.nih.gov/pubmed/35289444
http://dx.doi.org/10.1111/joim.13479

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