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In Vitro Efficacy and Molecular Mechanism of Curcumin Analog in Pathological Regulation of Spinocerebellar Ataxia Type 3

Unlike other nuclear factor erythroid-2-related factor 2 (Nrf2) activators, the mechanism of action of curcumin analog, ASC-JM17 (JM17), in regulating oxidative homeostasis remains unknown. Spinocerebellar ataxia type 3 (SCA3) is an inherited polyglutamine neurodegenerative disease caused mainly by...

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Detalles Bibliográficos
Autores principales:	Wu, Yu-Ling, Chang, Jui-Chih, Chao, Yi-Chun, Chan, Hardy, Hsieh, Mingli, Liu, Chin-San
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311745/ https://www.ncbi.nlm.nih.gov/pubmed/35883884 http://dx.doi.org/10.3390/antiox11071389

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