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Recent Advances in Silica-Nanomaterial-Assisted Lateral Flow Assay
Lateral flow assays (LFAs) have attracted much attention as rapid and affordable point-of-care devices for medical diagnostics. The global SARS-CoV-2 pandemic has further highlighted the importance of LFAs. Many efforts have been made to enhance the sensitivity of LFAs. In recent years, silica nanom...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311751/ https://www.ncbi.nlm.nih.gov/pubmed/35877318 http://dx.doi.org/10.3390/bioengineering9070266 |
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author | Zhuang, Han Xu, Chun Gao, Fang Li, Yiwei Lei, Chang Yu, Chengzhong |
author_facet | Zhuang, Han Xu, Chun Gao, Fang Li, Yiwei Lei, Chang Yu, Chengzhong |
author_sort | Zhuang, Han |
collection | PubMed |
description | Lateral flow assays (LFAs) have attracted much attention as rapid and affordable point-of-care devices for medical diagnostics. The global SARS-CoV-2 pandemic has further highlighted the importance of LFAs. Many efforts have been made to enhance the sensitivity of LFAs. In recent years, silica nanomaterials have been used to either amplify the signal of label materials or provide stability, resulting in better detection performance. In this review, the recent progress of silica-nanomaterial-assisted LFAs is summarized. The impact of the structure of silica nanomaterials on LFA performance, the challenges and prospects in this research area are also discussed. |
format | Online Article Text |
id | pubmed-9311751 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-93117512022-07-26 Recent Advances in Silica-Nanomaterial-Assisted Lateral Flow Assay Zhuang, Han Xu, Chun Gao, Fang Li, Yiwei Lei, Chang Yu, Chengzhong Bioengineering (Basel) Review Lateral flow assays (LFAs) have attracted much attention as rapid and affordable point-of-care devices for medical diagnostics. The global SARS-CoV-2 pandemic has further highlighted the importance of LFAs. Many efforts have been made to enhance the sensitivity of LFAs. In recent years, silica nanomaterials have been used to either amplify the signal of label materials or provide stability, resulting in better detection performance. In this review, the recent progress of silica-nanomaterial-assisted LFAs is summarized. The impact of the structure of silica nanomaterials on LFA performance, the challenges and prospects in this research area are also discussed. MDPI 2022-06-21 /pmc/articles/PMC9311751/ /pubmed/35877318 http://dx.doi.org/10.3390/bioengineering9070266 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Zhuang, Han Xu, Chun Gao, Fang Li, Yiwei Lei, Chang Yu, Chengzhong Recent Advances in Silica-Nanomaterial-Assisted Lateral Flow Assay |
title | Recent Advances in Silica-Nanomaterial-Assisted Lateral Flow Assay |
title_full | Recent Advances in Silica-Nanomaterial-Assisted Lateral Flow Assay |
title_fullStr | Recent Advances in Silica-Nanomaterial-Assisted Lateral Flow Assay |
title_full_unstemmed | Recent Advances in Silica-Nanomaterial-Assisted Lateral Flow Assay |
title_short | Recent Advances in Silica-Nanomaterial-Assisted Lateral Flow Assay |
title_sort | recent advances in silica-nanomaterial-assisted lateral flow assay |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311751/ https://www.ncbi.nlm.nih.gov/pubmed/35877318 http://dx.doi.org/10.3390/bioengineering9070266 |
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