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Recent Advances in Silica-Nanomaterial-Assisted Lateral Flow Assay

Lateral flow assays (LFAs) have attracted much attention as rapid and affordable point-of-care devices for medical diagnostics. The global SARS-CoV-2 pandemic has further highlighted the importance of LFAs. Many efforts have been made to enhance the sensitivity of LFAs. In recent years, silica nanom...

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Autores principales: Zhuang, Han, Xu, Chun, Gao, Fang, Li, Yiwei, Lei, Chang, Yu, Chengzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311751/
https://www.ncbi.nlm.nih.gov/pubmed/35877318
http://dx.doi.org/10.3390/bioengineering9070266
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author Zhuang, Han
Xu, Chun
Gao, Fang
Li, Yiwei
Lei, Chang
Yu, Chengzhong
author_facet Zhuang, Han
Xu, Chun
Gao, Fang
Li, Yiwei
Lei, Chang
Yu, Chengzhong
author_sort Zhuang, Han
collection PubMed
description Lateral flow assays (LFAs) have attracted much attention as rapid and affordable point-of-care devices for medical diagnostics. The global SARS-CoV-2 pandemic has further highlighted the importance of LFAs. Many efforts have been made to enhance the sensitivity of LFAs. In recent years, silica nanomaterials have been used to either amplify the signal of label materials or provide stability, resulting in better detection performance. In this review, the recent progress of silica-nanomaterial-assisted LFAs is summarized. The impact of the structure of silica nanomaterials on LFA performance, the challenges and prospects in this research area are also discussed.
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spelling pubmed-93117512022-07-26 Recent Advances in Silica-Nanomaterial-Assisted Lateral Flow Assay Zhuang, Han Xu, Chun Gao, Fang Li, Yiwei Lei, Chang Yu, Chengzhong Bioengineering (Basel) Review Lateral flow assays (LFAs) have attracted much attention as rapid and affordable point-of-care devices for medical diagnostics. The global SARS-CoV-2 pandemic has further highlighted the importance of LFAs. Many efforts have been made to enhance the sensitivity of LFAs. In recent years, silica nanomaterials have been used to either amplify the signal of label materials or provide stability, resulting in better detection performance. In this review, the recent progress of silica-nanomaterial-assisted LFAs is summarized. The impact of the structure of silica nanomaterials on LFA performance, the challenges and prospects in this research area are also discussed. MDPI 2022-06-21 /pmc/articles/PMC9311751/ /pubmed/35877318 http://dx.doi.org/10.3390/bioengineering9070266 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Zhuang, Han
Xu, Chun
Gao, Fang
Li, Yiwei
Lei, Chang
Yu, Chengzhong
Recent Advances in Silica-Nanomaterial-Assisted Lateral Flow Assay
title Recent Advances in Silica-Nanomaterial-Assisted Lateral Flow Assay
title_full Recent Advances in Silica-Nanomaterial-Assisted Lateral Flow Assay
title_fullStr Recent Advances in Silica-Nanomaterial-Assisted Lateral Flow Assay
title_full_unstemmed Recent Advances in Silica-Nanomaterial-Assisted Lateral Flow Assay
title_short Recent Advances in Silica-Nanomaterial-Assisted Lateral Flow Assay
title_sort recent advances in silica-nanomaterial-assisted lateral flow assay
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9311751/
https://www.ncbi.nlm.nih.gov/pubmed/35877318
http://dx.doi.org/10.3390/bioengineering9070266
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