Cargando…

Puerarin Attenuates Oxidative Stress and Ferroptosis via AMPK/PGC1α/Nrf2 Pathway after Subarachnoid Hemorrhage in Rats

Puerarin was shown to exert anti-oxidative and anti-ferroptosis effects in multiple diseases. The goal of this study was to explore the neuroprotective effect of puerarin on early brain injury (EBI) after subarachnoid hemorrhage (SAH) in rats. A total of 177 adult male Sprague Dawley rats were used....

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Yi, Wu, Honggang, Hu, Yongmei, Zhou, Chenhui, Wu, Jiawei, Wu, Yiwen, Wang, Haifeng, Lenahan, Cameron, Huang, Lei, Nie, Sheng, Gao, Xiang, Sun, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312059/ https://www.ncbi.nlm.nih.gov/pubmed/35883750 http://dx.doi.org/10.3390/antiox11071259

Ejemplares similares

The mechanism of ferroptosis in early brain injury after subarachnoid hemorrhage
por: Deng, Xinpeng, et al.
Publicado: (2023)

Melanocortin 1 receptor attenuates early brain injury following subarachnoid hemorrhage by controlling mitochondrial metabolism via AMPK/SIRT1/PGC-1α pathway in rats
por: Xu, Weilin, et al.
Publicado: (2021)

Validation and Comparison of Aneurysmal Subarachnoid Hemorrhage Grading Scales in Angiogram-Negative Subarachnoid Hemorrhage Patients
por: Fang, Yuanjian, et al.
Publicado: (2020)

Biological Effects and Mechanisms of Caspases in Early Brain Injury after Subarachnoid Hemorrhage
por: Wu, Yiwen, et al.
Publicado: (2022)

Puerarin protects against sepsis-induced myocardial injury through AMPK-mediated ferroptosis signaling
por: Zhou, Bin, et al.
Publicado: (2022)

Astragaloside IV attenuates ferroptosis after subarachnoid hemorrhage via Nrf2/HO-1 signaling pathway
por: Liu, Zhuanghua, et al.
Publicado: (2022)

The role of the astrocyte in subarachnoid hemorrhage and its therapeutic implications
por: Li, Rong, et al.
Publicado: (2022)

Comparison of aneurysmal subarachnoid hemorrhage grading scores in patients with aneurysm clipping and coiling
por: Fang, Yuanjian, et al.
Publicado: (2020)

The Updated Role of the Blood Brain Barrier in Subarachnoid Hemorrhage: From Basic and Clinical Studies
por: Chen, Sheng, et al.
Publicado: (2020)

Activation of SIRT1 Alleviates Ferroptosis in the Early Brain Injury after Subarachnoid Hemorrhage
por: Yuan, Bin, et al.
Publicado: (2022)

New Mechanisms and Targets of Subarachnoid Hemorrhage: A Focus on Mitochondria
por: Zhang, Zeyu, et al.
Publicado: (2022)

Heat shock protein 22 modulates NRF1/TFAM-dependent mitochondrial biogenesis and DRP1-sparked mitochondrial apoptosis through AMPK-PGC1α signaling pathway to alleviate the early brain injury of subarachnoid hemorrhage in rats
por: Fan, Haiyan, et al.
Publicado: (2021)

Ferroptosis is essential for diabetic cardiomyopathy and is prevented by sulforaphane via AMPK/NRF2 pathways
por: Wang, Xiang, et al.
Publicado: (2022)

Puerarin Induces Molecular Details of Ferroptosis-Associated Anti-Inflammatory on RAW264.7 Macrophages
por: Zeng, Jinzi, et al.
Publicado: (2022)

Pharmacological Modulations of Nrf2 and Therapeutic Implications in Aneurysmal Subarachnoid Hemorrhage
por: Zhang, Qia, et al.
Publicado: (2023)

Aquaporin 4 Depolarization-Enhanced Transferrin Infiltration Leads to Neuronal Ferroptosis after Subarachnoid Hemorrhage in Mice
por: Liu, Yuan, et al.
Publicado: (2022)

Herba houttuyniae Extract Benefits Hyperlipidemic Mice via Activation of the AMPK/PGC-1α/Nrf2 Cascade
por: Cao, Ke, et al.
Publicado: (2020)

Connection between oxidative stress and subcellular organelle in subarachnoid hemorrhage: Novel mechanisms and therapeutic implications
por: Zhang, Jiahao, et al.
Publicado: (2023)

Development of a nomogram for predicting clinical outcome in patients with angiogram‐negative subarachnoid hemorrhage
por: Zhang, Anke, et al.
Publicado: (2021)

Sestrin2 provides cerebral protection through activation of Nrf2 signaling in microglia following subarachnoid hemorrhage
por: Yang, Youqing, et al.
Publicado: (2023)

Baicalin suppresses autophagy-dependent ferroptosis in early brain injury after subarachnoid hemorrhage
por: Zheng, Bao, et al.
Publicado: (2021)

Puerarin ameliorates metabolic dysfunction-associated fatty liver disease by inhibiting ferroptosis and inflammation
por: Yang, Mengmeng, et al.
Publicado: (2023)

The emerging roles of MAPK-AMPK in ferroptosis regulatory network
por: Wang, Xinyue, et al.
Publicado: (2023)

A Novel Necroptosis-Related Prognostic Signature of Glioblastoma Based on Transcriptomics Analysis and Single Cell Sequencing Analysis
por: Wu, Yiwen, et al.
Publicado: (2022)

Vitamin C Sensitizes Pancreatic Cancer Cells to Erastin-Induced Ferroptosis by Activating the AMPK/Nrf2/HMOX1 Pathway
por: Liu, Yawen, et al.
Publicado: (2022)

New Insights of Early Brain Injury after Subarachnoid Hemorrhage: A Focus on the Caspase Family
por: Wang, Xiaoyu, et al.
Publicado: (2023)

Stimulator of IFN genes mediates neuroinflammatory injury by suppressing AMPK signal in experimental subarachnoid hemorrhage
por: Peng, Yucong, et al.
Publicado: (2020)

Puerarin increases the chemosensitivity of hepatocellular carcinoma cells
por: Wu, Zhen, et al.
Publicado: (2017)

Effect of stress‐induced hyperglycemia after non‐traumatic non‐aneurysmal subarachnoid hemorrhage on clinical complications and functional outcomes
por: Zhang, Zeyu, et al.
Publicado: (2022)

SIRT3 protects against early brain injury following subarachnoid hemorrhage via promoting mitochondrial fusion in an AMPK dependent manner
por: Wu, Xun, et al.
Publicado: (2020)

Bakuchiol Attenuates Oxidative Stress and Neuron Damage by Regulating Trx1/TXNIP and the Phosphorylation of AMPK After Subarachnoid Hemorrhage in Mice
por: Liu, Haixiao, et al.
Publicado: (2020)

Broccoli-Derived Glucoraphanin Activates AMPK/PGC1α/NRF2 Pathway and Ameliorates Dextran-Sulphate-Sodium-Induced Colitis in Mice
por: Tian, Qiyu, et al.
Publicado: (2022)

Effects of puerarin on the pharmacokinetics of triptolide in rats
por: Wang, Qingfa, et al.
Publicado: (2019)

Massive traumatic subarachnoid hemorrhage mimicking aneurysmal subarachnoid hemorrhage
por: El Mohamad, Amr Rachid, et al.
Publicado: (2023)

Triptolide promotes ferroptosis by suppressing Nrf2 to overcome leukemia cell resistance to doxorubicin
por: Wu, Xia, et al.
Publicado: (2022)

Role of hydrogen sulfide in subarachnoid hemorrhage
por: Lu, Dengfeng, et al.
Publicado: (2022)

Neuronal ferroptosis after intracerebral hemorrhage
por: Ren, Siying, et al.
Publicado: (2022)

Diallyl trisulfide alleviates chemotherapy sensitivity of ovarian cancer via the AMPK/SIRT1/PGC1α pathway
por: Wang, Zhaojun, et al.
Publicado: (2022)

The protective mechanism of protein kinase R to inhibit neuronal ferroptosis in cerebral injury from subarachnoid hemorrhage
por: Lei, Jianwei, et al.
Publicado: (2022)

Puerarin Inhibits Ferroptosis and Inflammation of Lung Injury Caused by Sepsis in LPS Induced Lung Epithelial Cells
por: Xu, Baiye, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_kj6in6eqb7lg7ip3qb7nq0p8pv