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Demethylation of H3K9 and H3K27 Contributes to the Tubular Renal Damage Triggered by Endoplasmic Reticulum Stress

Loss of protein homeostasis (proteostasis) in the endoplasmic reticulum (ER) activates the unfolded protein response (UPR), restoring correct protein folding. Sustained ER stress exacerbates activation of the major UPR branches (IRE1α/XBP1, PERK/ATF4, ATF6), inducing expression of numerous genes inv...

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Detalles Bibliográficos
Autores principales: Diaz-Bulnes, Paula, Saiz, Maria Laura, Corte-Iglesias, Viviana, Rodrigues-Diez, Raúl R, Bernardo Florez, Aida, Ruiz Bernet, Cristian, Martin Martin, Cristina, Ruiz-Ortega, Marta, Suarez-Alvarez, Beatriz, López-Larrea, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312208/
https://www.ncbi.nlm.nih.gov/pubmed/35883846
http://dx.doi.org/10.3390/antiox11071355