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Nature-Inspired Hybrids (NIH) Improve Proteostasis by Activating Nrf2-Mediated Protective Pathways in Retinal Pigment Epithelial Cells

Antioxidant systems play key roles in many elderly diseases, including age-related macular degeneration (AMD). Oxidative stress, autophagy impairment and inflammation are well-described in AMD, especially in retinal pigment epithelial (RPE) cells. The master regulator of antioxidant defense Nrf2 has...

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Detalles Bibliográficos
Autores principales:	Koskela, Ali, Manai, Federico, Basagni, Filippo, Liukkonen, Mikko, Rosini, Michela, Govoni, Stefano, Monte, Massimo Dal, Smedowski, Adrian, Kaarniranta, Kai, Amadio, Marialaura
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312215/ https://www.ncbi.nlm.nih.gov/pubmed/35883876 http://dx.doi.org/10.3390/antiox11071385

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