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Biomechanics of Transcatheter Aortic Valve Implant

Transcatheter aortic valve implantation (TAVI) has grown exponentially within the cardiology and cardiac surgical spheres. It has now become a routine approach for treating aortic stenosis. Several concerns have been raised about TAVI in comparison to conventional surgical aortic valve replacement (...

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Autores principales: Nappi, Francesco, Avtaar Singh, Sanjeet Singh, Nappi, Pierluigi, Fiore, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312295/
https://www.ncbi.nlm.nih.gov/pubmed/35877350
http://dx.doi.org/10.3390/bioengineering9070299
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author Nappi, Francesco
Avtaar Singh, Sanjeet Singh
Nappi, Pierluigi
Fiore, Antonio
author_facet Nappi, Francesco
Avtaar Singh, Sanjeet Singh
Nappi, Pierluigi
Fiore, Antonio
author_sort Nappi, Francesco
collection PubMed
description Transcatheter aortic valve implantation (TAVI) has grown exponentially within the cardiology and cardiac surgical spheres. It has now become a routine approach for treating aortic stenosis. Several concerns have been raised about TAVI in comparison to conventional surgical aortic valve replacement (SAVR). The primary concerns regard the longevity of the valves. Several factors have been identified which may predict poor outcomes following TAVI. To this end, the lesser-used finite element analysis (FEA) was used to quantify the properties of calcifications which affect TAVI valves. This method can also be used in conjunction with other integrated software to ascertain the functionality of these valves. Other imaging modalities such as multi-detector row computed tomography (MDCT) are now widely available, which can accurately size aortic valve annuli. This may help reduce the incidence of paravalvular leaks and regurgitation which may necessitate further intervention. Structural valve degeneration (SVD) remains a key factor, with varying results from current studies. The true incidence of SVD in TAVI compared to SAVR remains unclear due to the lack of long-term data. It is now widely accepted that both are part of the armamentarium and are not mutually exclusive. Decision making in terms of appropriate interventions should be undertaken via shared decision making involving heart teams.
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spelling pubmed-93122952022-07-26 Biomechanics of Transcatheter Aortic Valve Implant Nappi, Francesco Avtaar Singh, Sanjeet Singh Nappi, Pierluigi Fiore, Antonio Bioengineering (Basel) Review Transcatheter aortic valve implantation (TAVI) has grown exponentially within the cardiology and cardiac surgical spheres. It has now become a routine approach for treating aortic stenosis. Several concerns have been raised about TAVI in comparison to conventional surgical aortic valve replacement (SAVR). The primary concerns regard the longevity of the valves. Several factors have been identified which may predict poor outcomes following TAVI. To this end, the lesser-used finite element analysis (FEA) was used to quantify the properties of calcifications which affect TAVI valves. This method can also be used in conjunction with other integrated software to ascertain the functionality of these valves. Other imaging modalities such as multi-detector row computed tomography (MDCT) are now widely available, which can accurately size aortic valve annuli. This may help reduce the incidence of paravalvular leaks and regurgitation which may necessitate further intervention. Structural valve degeneration (SVD) remains a key factor, with varying results from current studies. The true incidence of SVD in TAVI compared to SAVR remains unclear due to the lack of long-term data. It is now widely accepted that both are part of the armamentarium and are not mutually exclusive. Decision making in terms of appropriate interventions should be undertaken via shared decision making involving heart teams. MDPI 2022-07-04 /pmc/articles/PMC9312295/ /pubmed/35877350 http://dx.doi.org/10.3390/bioengineering9070299 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Nappi, Francesco
Avtaar Singh, Sanjeet Singh
Nappi, Pierluigi
Fiore, Antonio
Biomechanics of Transcatheter Aortic Valve Implant
title Biomechanics of Transcatheter Aortic Valve Implant
title_full Biomechanics of Transcatheter Aortic Valve Implant
title_fullStr Biomechanics of Transcatheter Aortic Valve Implant
title_full_unstemmed Biomechanics of Transcatheter Aortic Valve Implant
title_short Biomechanics of Transcatheter Aortic Valve Implant
title_sort biomechanics of transcatheter aortic valve implant
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312295/
https://www.ncbi.nlm.nih.gov/pubmed/35877350
http://dx.doi.org/10.3390/bioengineering9070299
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