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Concentration-Dependent Activity of Pazufloxacin against Pseudomonas aeruginosa: An In Vivo Pharmacokinetic/Pharmacodynamic Study

The bacterium Pseudomonas aeruginosa is known to be associated with nosocomial infections around the world. Pazufloxacin, a potent DNA gyrase inhibitor, is known to be an effective drug candidate. However, it has not been clarified whether the pharmacokinetic (PK)/pharmacodynamic (PD) of pazufloxaci...

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Detalles Bibliográficos
Autores principales:	Umezaki, Yasuhiro, Matsumoto, Kazuaki, Ikawa, Kazuro, Yokoyama, Yuta, Enoki, Yuki, Shigemi, Akari, Watanabe, Erika, Nakamura, Koyo, Ueno, Keiichiro, Terazono, Hideyuki, Morikawa, Norifumi, Takeda, Yasuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312304/ https://www.ncbi.nlm.nih.gov/pubmed/35884236 http://dx.doi.org/10.3390/antibiotics11070982

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