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Impact of Ca(2+)-Induced PI(4,5)P(2) Clusters on PH-YFP Organization and Protein-Protein Interactions

Despite its low abundance, phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)) is a key modulator of membrane-associated signaling events in eukaryotic cells. Temporal and spatial regulation of PI(4,5)P(2) concentration can achieve localized increases in the levels of this lipid, which are crucial f...

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Detalles Bibliográficos
Autores principales: Borges-Araújo, Luís, Monteiro, Marina E., Mil-Homens, Dalila, Bernardes, Nuno, Sarmento, Maria J., Coutinho, Ana, Prieto, Manuel, Fernandes, Fábio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312469/
https://www.ncbi.nlm.nih.gov/pubmed/35883468
http://dx.doi.org/10.3390/biom12070912