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Bcl10 Regulates Lipopolysaccharide-Induced Pro-Fibrotic Signaling in Bronchial Fibroblasts from Severe Asthma Patients

Subepithelial fibrosis is a characteristic hallmark of airway remodeling in asthma. Current asthma medications have limited efficacy in treating fibrosis, particularly in patients with severe asthma, necessitating a deeper understanding of the fibrotic mechanisms. The NF-κB pathway is key to airway...

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Detalles Bibliográficos
Autores principales: Ramakrishnan, Rakhee K., Bajbouj, Khuloud, Guimei, Maha, Rawat, Surendra Singh, Kalaji, Zaina, Hachim, Mahmood Y., Mahboub, Bassam, Ibrahim, Saleh M., Hamoudi, Rifat, Halwani, Rabih, Hamid, Qutayba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312497/
https://www.ncbi.nlm.nih.gov/pubmed/35885021
http://dx.doi.org/10.3390/biomedicines10071716