Epithelial-Mesenchymal Plasticity Induced by Discontinuous Exposure to TGFβ1 Promotes Tumour Growth

SIMPLE SUMMARY: In this manuscript, we used a non-genetically manipulated EMT/MET cell line model to demonstrate that epithelial mesenchymal plasticity occurring in normal cells generates co-existing phenotypically and functionally divergent cell subpopulations which result in fast growing tumours i...

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Detalles Bibliográficos
Autores principales: Santos, Mafalda, Ferreira, Marta, Oliveira, Patrícia, Mendes, Nuno, André, Ana, Vieira, André F., Nunes, Joana B., Carvalho, Joana, Rocha, Sara, Azevedo, Mafalda, Ferreira, Daniel, Reis, Inês, Vinagre, João, Paredes, Joana, Heravi-Moussavi, Alireza, Lima, Jorge, Máximo, Valdemar, Burleigh, Angela, Roskelley, Calvin, Carneiro, Fátima, Huntsman, David, Oliveira, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312510/
https://www.ncbi.nlm.nih.gov/pubmed/36101425
http://dx.doi.org/10.3390/biology11071046

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