Cargando…

Chrysin Induces Apoptosis and Autophagy in Human Melanoma Cells via the mTOR/S6K Pathway

Chrysin is known to exert anti-inflammatory, antioxidant, and anticancer effects. The aim of this study was to investigate the anticancer effects of chrysin in the human melanoma cells A375SM and A375P. The results obtained demonstrated successful inhibition of the viability of these cells by induci...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Jae-Han, Yoo, Eun-Seon, Han, So-Hee, Jung, Gi-Hwan, Han, Eun-Ji, Choi, Eun-Young, Jeon, Su-ji, Jung, Soo-Hyun, Kim, Bumseok, Cho, Sung-Dae, Nam, Jeong-Seok, Choi, Changsun, Che, Jeong-Hwan, Jung, Ji-Youn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312811/ https://www.ncbi.nlm.nih.gov/pubmed/35884773 http://dx.doi.org/10.3390/biomedicines10071467

Ejemplares similares

Chrysin Induces Apoptosis via the MAPK Pathway and Regulates ERK/mTOR-Mediated Autophagy in MC-3 Cells
por: Jung, Gi-Hwan, et al.
Publicado: (2022)

Myricetin induces apoptosis and autophagy in human gastric cancer cells through inhibition of the PI3K/Akt/mTOR pathway
por: Han, So-Hee, et al.
Publicado: (2022)

Myricetin induces apoptosis through the MAPK pathway and regulates JNK-mediated autophagy in SK-BR-3 cells
por: Han, So-Hee, et al.
Publicado: (2022)

Piperlongumine induces apoptosis via the MAPK pathway and ERK-mediated autophagy in human melanoma cells
por: Jeon, Su-Ji, et al.
Publicado: (2023)

Inhibition of DNMT3B and PI3K/AKT/mTOR and ERK Pathways as a Novel Mechanism of Volasertib on Hypomethylating Agent-Resistant Cells
por: Choi, Eun-Ji, et al.
Publicado: (2023)

Subacute Oral Toxicity Evaluation of Expanded-Polystyrene-Fed Tenebrio molitor Larvae (Yellow Mealworm) Powder in Sprague-Dawley Rats
por: Choi, Eun-Young, et al.
Publicado: (2022)

Piperlongumine Induces Apoptosis and Cytoprotective Autophagy via the MAPK Signaling Pathway in Human Oral Cancer Cells
por: Choi, Eun-Young, et al.
Publicado: (2023)

Chrysin Increases the Therapeutic Efficacy of Docetaxel and Mitigates Docetaxel-Induced Edema
por: Lim, Hyun-Kyung, et al.
Publicado: (2016)

Piperine Induces Apoptosis and Autophagy in HSC-3 Human Oral Cancer Cells by Regulating PI3K Signaling Pathway
por: Han, Eun-Ji, et al.
Publicado: (2023)

SPHK/HIF-1α Signaling Pathway Has a Critical Role in Chrysin-Induced Anticancer Activity in Hypoxia-Induced PC-3 Cells
por: Han, Hengmin, et al.
Publicado: (2022)

Inhibitory Effect of mTOR Activator MHY1485 on Autophagy: Suppression of Lysosomal Fusion
por: Choi, Yeon Ja, et al.
Publicado: (2012)

Correction: Inhibitory Effect of mTOR Activator MHY1485 on Autophagy: Suppression of Lysosomal Fusion
por: Choi, Yeon Ja, et al.
Publicado: (2013)

Chrysin induces autophagy through the inactivation of the ROS-mediated Akt/mTOR signaling pathway in endometrial cancer
por: He, Yu, et al.
Publicado: (2021)

Shikonin inhibits proliferation of melanoma cells by MAPK pathway-mediated induction of apoptosis
por: Lee, Jae Han, et al.
Publicado: (2021)

Bee Venom Triggers Autophagy-Induced Apoptosis in Human Lung Cancer Cells via the mTOR Signaling Pathway
por: Yu, Ji Eun, et al.
Publicado: (2022)

Dual-Blocking of PI3K and mTOR Improves Chemotherapeutic Effects on SW620 Human Colorectal Cancer Stem Cells by Inducing Differentiation
por: Kim, Min-Jung, et al.
Publicado: (2016)

Decursin and Doxorubicin Are in Synergy for the Induction of Apoptosis via STAT3 and/or mTOR Pathways in Human Multiple Myeloma Cells
por: Jang, Jinsil, et al.
Publicado: (2013)

Apigenin induces apoptosis by regulating Akt and MAPK pathways in human melanoma cell A375SM
por: Woo, Joong-Seok, et al.
Publicado: (2020)

Dual Inhibition of PI3K/Akt/mTOR Pathway and Role of Autophagy in Non-Small Cell Lung Cancer Cells
por: Jeong, Eun-Hui, et al.
Publicado: (2012)

Antiviral Activity of Chrysin against Influenza Virus Replication via Inhibition of Autophagy
por: Kim, Seong-Ryeol, et al.
Publicado: (2021)

Crosstalk between Autophagy and Inflammatory Processes in Cancer
por: Lee, Eun-Ji, et al.
Publicado: (2021)

Apoptotic effect of tolfenamic acid on MDA-MB-231 breast cancer cells and xenograft tumors
por: Kim, Hyeong-Jin, et al.
Publicado: (2013)

Single-Cell RNA Sequencing Reveals Immuno-Oncology Characteristics of Tumor-Infiltrating T Lymphocytes in Photodynamic Therapy-Treated Colorectal Cancer Mouse Model
por: Lee, Eun-Ji, et al.
Publicado: (2023)

Dietary Compound Chrysin Inhibits Retinal Neovascularization with Abnormal Capillaries in db/db Mice
por: Kang, Min-Kyung, et al.
Publicado: (2016)

Pharmacokinetic Interaction of Chrysin with Caffeine in Rats
por: Noh, Keumhan, et al.
Publicado: (2016)

Right iliac arterial aneurysm in a 4-year-old girl who does not have a right external iliac artery
por: Lee, Jeong-Hwan, et al.
Publicado: (2016)

mTOR-Mediated Antioxidant Activation in Solid Tumor Radioresistance
por: Woo, Yunseo, et al.
Publicado: (2019)

mTOR and ROS regulation by anethole on adipogenic differentiation in human mesenchymal stem cells
por: Rhee, Yun-Hee, et al.
Publicado: (2018)

Association between Patients’ Self-Judgement, Coagulated Menstrual Blood, and Menorrhagia: Results from a Questionnaire Survey and Blood Test Analysis
por: Lee, Eun Ji, et al.
Publicado: (2023)

mTOR, autophagy, and reprogramming
por: Tang, Bor Luen
Publicado: (2014)

Comparison of murine retroorbital plexus and facial vein blood collection to mitigate animal ethics issues
por: Jo, Eun Jung, et al.
Publicado: (2021)

Autophagy Inhibition with Monensin Enhances Cell Cycle Arrest and Apoptosis Induced by mTOR or Epidermal Growth Factor Receptor Inhibitors in Lung Cancer Cells
por: Choi, Hyeong Sim, et al.
Publicado: (2013)

Modulation of specificity protein 1 by mithramycin A as a novel therapeutic strategy for cervical cancer
por: Choi, Eun-Sun, et al.
Publicado: (2014)

Development and Evaluation of a Hospice and Palliative Care Music Therapy Education Program
por: Kim, Eun Jung, et al.
Publicado: (2020)

Non-compliance with pregnancy prevention recommendations for isotretinoin in Korea between 2019–2020
por: Choi, Eun Jeong, et al.
Publicado: (2021)

Evaluation of Deodorizing Effects of Saccharina japonica in 10-Month-Old ICR Mice Using a Novel Odor Marker Associated with Aging
por: Kim, Ji Eun, et al.
Publicado: (2022)

Dietary Chrysin Suppresses Formation of Actin Cytoskeleton and Focal Adhesion in AGE-Exposed Mesangial Cells and Diabetic Kidney: Role of Autophagy
por: Lee, Eun-Jung, et al.
Publicado: (2019)

Two-Dimensional rGO-MoS(2) Hybrid Additives for High-Performance Magnetorheological Fluid
por: Manzoor, Muhammad Taha, et al.
Publicado: (2018)

mTOR-dependent dysregulation of autophagy contributes to the retinal ganglion cell loss in streptozotocin-induced diabetic retinopathy
por: Madrakhimov, Sanjar Batirovich, et al.
Publicado: (2021)

Effect of Herpes Zoster Treatment and Sudden Sensorineural Hearing Loss Using National Health Insurance Claims Data of South Korea
por: Son, Hyo Jung, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_98ov85hr9npckpkohj9g5m3b96