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The Mitochondrial HSP90 Paralog TRAP1: Structural Dynamics, Interactome, Role in Metabolic Regulation, and Inhibitors

The HSP90 paralog TRAP1 was discovered more than 20 years ago; yet, a detailed understanding of the function of this mitochondrial molecular chaperone remains elusive. The dispensable nature of TRAP1 in vitro and in vivo further complicates an understanding of its role in mitochondrial biology. TRAP...

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Detalles Bibliográficos
Autores principales:	Joshi, Abhinav, Ito, Takeshi, Picard, Didier, Neckers, Len
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312948/ https://www.ncbi.nlm.nih.gov/pubmed/35883436 http://dx.doi.org/10.3390/biom12070880

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