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The Upregulation of Caffeic Acid Phenethyl Ester on Growth Differentiation Factor 15 Inhibits Transforming Growth Factor β/Smad Signaling in Bladder Carcinoma Cells

Growth differentiation factor 15 (GDF15) is known as a TGFβ-like cytokine acting on the TGFβ receptor to modulate target genes. GDF15 is regarded as a tumor suppressor gene in the human bladder and the caffeic acid phenethyl ester (CAPE) induces GDF15 expression to inhibit the tumor growth in vitro...

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Detalles Bibliográficos
Autores principales: Hou, Chen-Pang, Tsui, Ke-Hung, Chen, Syue-Ting, Chang, Kang-Shuo, Sung, Hsin-Ching, Hsu, Shu-Yuan, Lin, Yu-Hsiang, Feng, Tsui-Hsia, Juang, Horng-Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9312961/
https://www.ncbi.nlm.nih.gov/pubmed/35884930
http://dx.doi.org/10.3390/biomedicines10071625

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